Objectives: Lower first molars are known to erupt ahead of other teeth during eruption of permanent dentition. But recently, a few countries have reported a change in this pattern. The present study determined the eruption sequence between lower permanent first molars and lower permanent central incisors in Nigerian Children. Methods: The study population consisted of 94 healthy Nigerian school children aged 4-7 years as at their last birthday, selected randomly from private and public nursery schools in Ibadan, Nigeria. Intra oral examination was done out door under natural lightening condition and only children who had either the lower permanent central incisor(s) or lower first permanent molar(s) were included in the study. The data was subjected to simple descriptive and statistical analysis using SPSS for windows version 11.0. Results: There were 48 boys and 46 girls in the study. Their mean age was 5.77+0.61 years. Sixty-seven percent of the children were 6 years old while 23.4% were 5 years old. Only 3.2% were 4years old. One hundred and seventy six teeth were erupted as at the time of the study and 62.5% were central incisors, while 37.5% were first molars. The lower central incisors erupted earlier in 56.38% of the children while the lower first molars erupted earlier in 43.62% of the children. Conclusion: A reversal in the eruption order of the lower first permanent molar and the lower permanent central incisor has been observed, whereby a higher percentage of the children were found to erupt their lower central incisors before lower permanent first molars.