IADR Abstract Archives
Mineral Gain by Molar Incisor Hipomineralization (MIH) After REFIX-Toothpaste Use
Objectives: The aim of this study was to evaluate the mineral gain of (moderate and severe) MIH lesions after a 30-day use of a bioactive Si-toothpaste containing REFIX technology.
Methods: This is a short-term (30-days) clinical study. After informal consent, four children (7-10 years old) with moderate or severe MIH lesions received professional prophylaxis with a fluoride-free toothpaste. Then, they were assessed (central incisors and first molars) using a photoinduced fluorescence quantification system (QLF, Inspektor Research Systems B.V., the Netherlands) (ΔF, baseline, t0-d0). Later, they brushed the teeth with a REFIX-toothpaste (1450 ppm, Dental Clean, Brazil) and potential mineral gain was assessed by QLF after 5 (ΔF-t5-d0) and 60 min (ΔF-t60-d0) of brushing. Children used REFIX-toothpaste twice a day for 30 days after the initiation of the study when they were examined in the morning after 12 h of the last brush and repeated the same procedures of baseline day: before brushing, 5 and 60 min after using a REFIX-toothpaste. The depth of the lesions was assessed using the ΔFMax parameter at the same times of data collection. Reduction of pain was assessed in two individuals using a visual analogue scale (0-10 points). Comparisons were carried out using mean, medians and non-parametric statistics (p<0.05).
Results: Mean (SD) ΔF values (mineral gain) of baseline (n=16 teeth) were -8.9 (16.2), -7.2 (13.8), -4.8 (10.2) for t0, t5 and t60 (p>0,01), respectively. These values after 30 days of REFIX-toothpaste use were -6.2(14.6), -5.2(13.5), -5.2 (12.7) for t0, t5 and t60 (p>0,01), respectively. The mean (SD) ΔFMax (lesion depth) in baseline day reduced from -14.3 (27.5) in t0 to -10.9 (27.9) in t60 (p>0,01). After 30 days these values were -10.4 (26.4) and -10.4 (27.0) for t0 and t60 (p>0,01), respectively. There was a significant reduction of pain VAS scale (values from 8.5 to 3.1 and from 7.0 to 2.2 points).
Conclusions: There was a numerical (but non-significant) mineral gain in MIH lesions after the use of REFIX-toothpastes immediately and after 30 days of use. The depth of lesion did not reduce significantly, remaining relatively the same after 30 days. There was a reduction of pain in two individuals providing a recovery of their quality of life.
Methods: This is a short-term (30-days) clinical study. After informal consent, four children (7-10 years old) with moderate or severe MIH lesions received professional prophylaxis with a fluoride-free toothpaste. Then, they were assessed (central incisors and first molars) using a photoinduced fluorescence quantification system (QLF, Inspektor Research Systems B.V., the Netherlands) (ΔF, baseline, t0-d0). Later, they brushed the teeth with a REFIX-toothpaste (1450 ppm, Dental Clean, Brazil) and potential mineral gain was assessed by QLF after 5 (ΔF-t5-d0) and 60 min (ΔF-t60-d0) of brushing. Children used REFIX-toothpaste twice a day for 30 days after the initiation of the study when they were examined in the morning after 12 h of the last brush and repeated the same procedures of baseline day: before brushing, 5 and 60 min after using a REFIX-toothpaste. The depth of the lesions was assessed using the ΔFMax parameter at the same times of data collection. Reduction of pain was assessed in two individuals using a visual analogue scale (0-10 points). Comparisons were carried out using mean, medians and non-parametric statistics (p<0.05).
Results: Mean (SD) ΔF values (mineral gain) of baseline (n=16 teeth) were -8.9 (16.2), -7.2 (13.8), -4.8 (10.2) for t0, t5 and t60 (p>0,01), respectively. These values after 30 days of REFIX-toothpaste use were -6.2(14.6), -5.2(13.5), -5.2 (12.7) for t0, t5 and t60 (p>0,01), respectively. The mean (SD) ΔFMax (lesion depth) in baseline day reduced from -14.3 (27.5) in t0 to -10.9 (27.9) in t60 (p>0,01). After 30 days these values were -10.4 (26.4) and -10.4 (27.0) for t0 and t60 (p>0,01), respectively. There was a significant reduction of pain VAS scale (values from 8.5 to 3.1 and from 7.0 to 2.2 points).
Conclusions: There was a numerical (but non-significant) mineral gain in MIH lesions after the use of REFIX-toothpastes immediately and after 30 days of use. The depth of lesion did not reduce significantly, remaining relatively the same after 30 days. There was a reduction of pain in two individuals providing a recovery of their quality of life.
IMAGES
4206753_File000000.jpg
4206753_File000001.jpg
4206753_File000000.jpg
4206753_File000001.jpg