IADR Abstract Archives
Dementia Correlates With Poorer Systemic Health in a Multi-Institutional Dataset
Objectives: Dementia is the decline in a person’s capability to remember day-to-day tasks. Dementia has been independently correlated to a higher incidence of oral health diseases, cardiovascular diseases (CVD), diabetes, and smoking habits. This study sought to find the correlation between dementia and multiple common comorbid conditions using a large and unique dataset in BigMouth, a multi-institutional dental data repository.
Methods: Deidentified health records in BigMouth were obtained from eight US dental schools (HSC-DB-21-0437). Patients (age > 50) with self-reported dementia or Alzheimer’s Disease were categorized as the dementia group (DG, N=1068). Two control group (CG) cohorts were matched with the DG for 1) age and gender (CG-AG N=1055); 2) age, gender, tobacco use, and diabetes (CG-AGSD, N=744). DG and CG were compared for the incidences of tobacco use, diabetes, CVD, angina, arrhythmias, arteriosclerosis, bypass surgery, congenital heart disease, coronary heart disease, heart attack, heart failure, heart problem, heart valve, high blood pressure, low blood pressure, high cholesterol, palpitation, peripheral edema, heart rheumatism, and shortness of breath. Data was analyzed using a chi-square test (P < 0.05).
Results: The incidence of CVD was higher in the DG, whereas diabetes and tobacco use were comparable in the CG-AG. The incidence of the CVD conditions angina, arrhythmia, coronary heart disease, heart failure, palpitations, peripheral edema, and shortness of breath was higher in the DG than the CG-AGSD. Interestingly, the incidence of high blood pressure was higher in CG-AGSD than DG. The rest of the parameters were comparable in CG-AGSD and DG.
Conclusions: The retrospective data analysis using Bigmouth shows that several cardiovascular diseases such as arrhythmias, angina, heart failure, and shortness of breath show a higher incidence in the dementia population. With rising dementia cases, further research is needed to identify the risk factors and dissect the causative links between systemic health and dementia.
Methods: Deidentified health records in BigMouth were obtained from eight US dental schools (HSC-DB-21-0437). Patients (age > 50) with self-reported dementia or Alzheimer’s Disease were categorized as the dementia group (DG, N=1068). Two control group (CG) cohorts were matched with the DG for 1) age and gender (CG-AG N=1055); 2) age, gender, tobacco use, and diabetes (CG-AGSD, N=744). DG and CG were compared for the incidences of tobacco use, diabetes, CVD, angina, arrhythmias, arteriosclerosis, bypass surgery, congenital heart disease, coronary heart disease, heart attack, heart failure, heart problem, heart valve, high blood pressure, low blood pressure, high cholesterol, palpitation, peripheral edema, heart rheumatism, and shortness of breath. Data was analyzed using a chi-square test (P < 0.05).
Results: The incidence of CVD was higher in the DG, whereas diabetes and tobacco use were comparable in the CG-AG. The incidence of the CVD conditions angina, arrhythmia, coronary heart disease, heart failure, palpitations, peripheral edema, and shortness of breath was higher in the DG than the CG-AGSD. Interestingly, the incidence of high blood pressure was higher in CG-AGSD than DG. The rest of the parameters were comparable in CG-AGSD and DG.
Conclusions: The retrospective data analysis using Bigmouth shows that several cardiovascular diseases such as arrhythmias, angina, heart failure, and shortness of breath show a higher incidence in the dementia population. With rising dementia cases, further research is needed to identify the risk factors and dissect the causative links between systemic health and dementia.