IADR Abstract Archives
Assessment of Silver&Fluoride in Sound-Enamel-Treated With SDF vs SDF/With Fluoride-Varnish
Objectives: Silver diamine fluoride (SDF) contains both silver and fluoride ions that are stabilized by diamine groups. SDF application provides sustained fluoride release which enhances tooth remineralization, while sustained silver release provides an anti-microbial effect. The purpose of this study was to investigate if concomitant fluoride-varnish (FV) application on top of SDF-treated dental enamel influences silver and fluoride sustainability in sound enamel.
Methods: Twelve sound extracted human molars were sectioned mesiodistally and apicogingivally into 24 facial and lingual coronal specimens. A 2x3 mm enamel treatment window was created by applying adhesive tape and coating the rest of the specimen with nail varnish. Specimens were randomly assigned into 2 groups: the SDF group treated with 38% SDF for 1 minute and the SDF-FV group treated with SDF followed by FV. Both groups were subjected to the Queiroz 9-day pH-cycling model protocol involving 8 days of demineralization-remineralization cycling, and a final remineralization cycle on day 9. Treated specimens were then carbon sputter-coated and analyzed using energy-dispersive x-ray spectroscopy to measure the average atomic percentages of residual silver (Ag) and fluoride (F).
Results: A nonparametric Mann-Whitney U test was used to compare both groups. There was no significant difference in the medians between the two treatment groups average atomic percentages for both Ag (p=0.478) and F (p=0.060) using a p-value of 0.05.
Conclusions: Within the constraints of the study, adding fluoride varnish over SDF did not improve Ag or F sustainability.
Methods: Twelve sound extracted human molars were sectioned mesiodistally and apicogingivally into 24 facial and lingual coronal specimens. A 2x3 mm enamel treatment window was created by applying adhesive tape and coating the rest of the specimen with nail varnish. Specimens were randomly assigned into 2 groups: the SDF group treated with 38% SDF for 1 minute and the SDF-FV group treated with SDF followed by FV. Both groups were subjected to the Queiroz 9-day pH-cycling model protocol involving 8 days of demineralization-remineralization cycling, and a final remineralization cycle on day 9. Treated specimens were then carbon sputter-coated and analyzed using energy-dispersive x-ray spectroscopy to measure the average atomic percentages of residual silver (Ag) and fluoride (F).
Results: A nonparametric Mann-Whitney U test was used to compare both groups. There was no significant difference in the medians between the two treatment groups average atomic percentages for both Ag (p=0.478) and F (p=0.060) using a p-value of 0.05.
Conclusions: Within the constraints of the study, adding fluoride varnish over SDF did not improve Ag or F sustainability.