Fluoride Release From a New Amalgam Replacement Material: Cention N
Objectives: A novel restorative material, Cention N (Ivoclar Vivadent, Amshert, NY), has been introduced to the market as an alternative to materials such as amalgam. Among its benefits, it has the potential to release fluoride into the oral environment, helping reduce the incidence of caries lesions. The aim of this in vitro study is to compare the fluoride ion release of Cention N with other restorative materials.
Methods: A custom-mold was used to create 5mm diameter and 2mm thick discs of each material tested: Cention N, a resin composite, Filtek One Bulk Fill (RBC) (3M,St. Paul MN), a glass ionomer restorative material GC EQUIA Forte (GC America Inc, Alsip IL), and SDI GS-80 amalgam (SDI, Itasca, IL). Samples were placed into 4 ml of two different media, RO water (pH = 7) and lactic acid (pH = 4). Fluoride ion-release was measured with an ion-selective electrode probe, (Orion, ThermoFisher Scientific) at 6 different time points after insertion: 24 hrs, 1 week, 2 weeks, 3 weeks, 4 weeks, and 8 weeks. Samples were kept in an incubator at 37°C between measurements. Data were compared using ANOVA with post-hoc Tukey (α=0.05). Results: Cention N resulted in significantly higher fluoride release than both the amalgam and resin composite, but the release was lower than the glass ionomer samples. Both the resin composite and amalgam samples had fluoride-release that was below the minimum detection limit. Within the first 24 hours, GC Equia displayed nearly double the fluoride ion concentration released by the Cention N discs. Conclusions: Compared to the other materials tested, Cention N released a higher fluoride concentration than the composite or the amalgam materials that it is designed to replace. However, Cention N had a lower ion-release than the glass ionomer material.