IADR Abstract Archives
Potential Erosive Assesment of Dry Mouth Lozenges and Tablets
Objectives: To measure the pH values, titratable acidity, and potential erosive effect of commercially available dry mouth lozenges and tablets and its effect on enamel and dentin.
Methods: A pH analysis was performed for nine dry mouth lozenges and tablets available () using a calibrated pH meter, and the neutralisable acidity was measured by titrating the lozenges/tabelts against 0.1M NaOH. In order to get a solution-like to specimens were dissolve in destilled water with a pH neutral. The gravimetric analysis was performed by submerging human enamel and dentin blocks specimens in 5 ml of each solution for a total of 2 weeks, measurements were recorded at base line, 24 hours, 48 hours, 96 hours, 1 week and 2 weeks. The difference between the nine specimens will be verified using non-parametric tests (Kruskall-Wallis and Mann-Whitney tests). The level of significance was set at 0.05.
Results: The mean pH values are as follow, Salese, Xylimelts and ACT exhibited a pH alkaline at 7.9, 7.9 and 7.1. Cotton mouth reported the lowest pH of 3.1 follow by Ora Moist at 3.6. CVS Dry Mouth and Rite Aid resulted in an acidic pH of 5.5 and 5.1. Smart Mouth and Thera Breath were close to the critical pH of dentin at 6.4 and 6.6. A significant correlation between pH and TA was observed for this dataset (p<0.0001). No difference between the groups was observed regarding enamel loss (p=0.0631). However, a significant difference was observed between the 9 specimens (p=0.0011).
Conclusions: In spite of the limitations of the in-vitro study,the authors concluded that some lozenges/tablets have a pH lower than the critical pH of enamel and dentin. There is a significant association between acidic pH values and higher titratable acidity. Some lozenges may have erosive potential on tooth structure.
Methods: A pH analysis was performed for nine dry mouth lozenges and tablets available () using a calibrated pH meter, and the neutralisable acidity was measured by titrating the lozenges/tabelts against 0.1M NaOH. In order to get a solution-like to specimens were dissolve in destilled water with a pH neutral. The gravimetric analysis was performed by submerging human enamel and dentin blocks specimens in 5 ml of each solution for a total of 2 weeks, measurements were recorded at base line, 24 hours, 48 hours, 96 hours, 1 week and 2 weeks. The difference between the nine specimens will be verified using non-parametric tests (Kruskall-Wallis and Mann-Whitney tests). The level of significance was set at 0.05.
Results: The mean pH values are as follow, Salese, Xylimelts and ACT exhibited a pH alkaline at 7.9, 7.9 and 7.1. Cotton mouth reported the lowest pH of 3.1 follow by Ora Moist at 3.6. CVS Dry Mouth and Rite Aid resulted in an acidic pH of 5.5 and 5.1. Smart Mouth and Thera Breath were close to the critical pH of dentin at 6.4 and 6.6. A significant correlation between pH and TA was observed for this dataset (p<0.0001). No difference between the groups was observed regarding enamel loss (p=0.0631). However, a significant difference was observed between the 9 specimens (p=0.0011).
Conclusions: In spite of the limitations of the in-vitro study,the authors concluded that some lozenges/tablets have a pH lower than the critical pH of enamel and dentin. There is a significant association between acidic pH values and higher titratable acidity. Some lozenges may have erosive potential on tooth structure.