IADR Abstract Archives
The Efficacy of Combining High-concentration Fluoride and Recaldent® Products
Objectives: The aim of this study was to evaluate the efficacy of the combination of high concentration fluoride products and a Casein phosphopeptide-Amorphous Calcium phosphate (CPP-ACP, Recaldent®) product.
Methods: The materials used in this study were MI Paste ONE (MIPO, GC), MI Varnish (MIV, GC) and Nupro APF Topical gel (APF, Dentsply). Sound enamel slabs from bovine maxillary incisors were used (n=8) for a pH-cycling test. Enamel surfaces were polished with SIC paper (#1500). The re/demineralization effect was investigated by the pH-cycling test for 5 days at 37 degree Celsius. MIV or APF were used only the first day at the beginning of the pH-cycling test. The re- or demineralization step was conducted for 6 or 18 hours respectively, including a 5-minute immersion of the specimens in 10% sample dilutions or distilled water (D.W.) and then immersing it in re- or demineralization solution for the remaining hours. After pH-cycling, the demineralization level was assessed by radiographic image analysis using X-ray CT (inspeXio SM X-100CT, SHIMAZU). The difference of areas of mineral profiles before and after pH-cycling were calculated as a mineral loss value (ΔZ). DW was used as a control. Data were statistically analyzed with ANOVA and Tukey tests (p<0.05).
Results: The ΔZ values (vol%*µm) of only MIPO (-174.52) and combination of MIPO and APF (-160.82) were significantly lower than the use of only APF (-271.95). The ΔE value of the combination of MIPO and APF was significantly lower than the use of only MIV (-263.54).
Conclusions: The combination of high concentration fluoride and MI Paste One is more effective at inhibiting demineralization than when only using high concentration fluoride alone.
Methods: The materials used in this study were MI Paste ONE (MIPO, GC), MI Varnish (MIV, GC) and Nupro APF Topical gel (APF, Dentsply). Sound enamel slabs from bovine maxillary incisors were used (n=8) for a pH-cycling test. Enamel surfaces were polished with SIC paper (#1500). The re/demineralization effect was investigated by the pH-cycling test for 5 days at 37 degree Celsius. MIV or APF were used only the first day at the beginning of the pH-cycling test. The re- or demineralization step was conducted for 6 or 18 hours respectively, including a 5-minute immersion of the specimens in 10% sample dilutions or distilled water (D.W.) and then immersing it in re- or demineralization solution for the remaining hours. After pH-cycling, the demineralization level was assessed by radiographic image analysis using X-ray CT (inspeXio SM X-100CT, SHIMAZU). The difference of areas of mineral profiles before and after pH-cycling were calculated as a mineral loss value (ΔZ). DW was used as a control. Data were statistically analyzed with ANOVA and Tukey tests (p<0.05).
Results: The ΔZ values (vol%*µm) of only MIPO (-174.52) and combination of MIPO and APF (-160.82) were significantly lower than the use of only APF (-271.95). The ΔE value of the combination of MIPO and APF was significantly lower than the use of only MIV (-263.54).
Conclusions: The combination of high concentration fluoride and MI Paste One is more effective at inhibiting demineralization than when only using high concentration fluoride alone.