IADR Abstract Archives
Association Between Apnea/Hypopnea Index and Cephalometric Airway Measurements
Objectives: Introduction: Obstructive sleep apnea (OSA) is a common and serious cause of metabolic, cardiovascular and neurocognitive morbidity in children. OSA is a complex disease arising from various factors including measurable intermediate phenotypes such as anatomical narrowing, neuromuscular compensation, ventilatory control stability, and arousal threshold.
The aim of this study was to explore the relationship between the obstructive respiratory disturbance index and different airway cephalometric measurements.
Methods: Method: This is a prospective, cross-sectional study that was conducted at the department of orthodontics at Harvard School of Dental Medicine. IRB approval was obtained and consents were taken from the 49 participants (mean age = 23.58, ages ranging from 11-69). Each participant underwent ambulatory testing with a Medibyte Jr. (portable sleep monitor) to estimate the severity of OSA. Measurements from the sleep monitor was analyzed to obtain an obstructive RDI score. In addition, routine orthodontic records consisting of 3-dimensional intra-oral scans and 2-dimensional lateral cephalograms was taken representing both dental and cephalometric airway, dental and skeletal measurements. The lateral cephalogram was traced and the airway measurements were noted. A linear regression model was conducted to examine the relationship between OSA and various airway measurement variables. The continuous outcome variable was obstructive RDI and the explanatory variables tested were the superior and middle airway space adjusted for gender, age, race, daily sleep hours, and BMI.
Results: Results: A significant inverse relation was detected between the superior airway space (measured as the width of the line from basion to gonion bisecting the posterior nasal spine to porion) and obstructive RDI (B= -0.6, P value < 0.05), adjusting for age, gender, race, daily sleep hours, and BMI.
Conclusions: Conclusion: In a convenience sample of orthodontic patients, individuals who have smaller superior airway space had a greater severity of obstructive sleep apnea.
The aim of this study was to explore the relationship between the obstructive respiratory disturbance index and different airway cephalometric measurements.
Methods: Method: This is a prospective, cross-sectional study that was conducted at the department of orthodontics at Harvard School of Dental Medicine. IRB approval was obtained and consents were taken from the 49 participants (mean age = 23.58, ages ranging from 11-69). Each participant underwent ambulatory testing with a Medibyte Jr. (portable sleep monitor) to estimate the severity of OSA. Measurements from the sleep monitor was analyzed to obtain an obstructive RDI score. In addition, routine orthodontic records consisting of 3-dimensional intra-oral scans and 2-dimensional lateral cephalograms was taken representing both dental and cephalometric airway, dental and skeletal measurements. The lateral cephalogram was traced and the airway measurements were noted. A linear regression model was conducted to examine the relationship between OSA and various airway measurement variables. The continuous outcome variable was obstructive RDI and the explanatory variables tested were the superior and middle airway space adjusted for gender, age, race, daily sleep hours, and BMI.
Results: Results: A significant inverse relation was detected between the superior airway space (measured as the width of the line from basion to gonion bisecting the posterior nasal spine to porion) and obstructive RDI (B= -0.6, P value < 0.05), adjusting for age, gender, race, daily sleep hours, and BMI.
Conclusions: Conclusion: In a convenience sample of orthodontic patients, individuals who have smaller superior airway space had a greater severity of obstructive sleep apnea.