IADR Abstract Archives
Effects of Paste/Gel Sequence on Post-Prophylaxis Stain, Calculus and Plaque
Objectives: A randomized controlled trial was conducted to assess the effectiveness of a daily 2-step dentifrice and gel system to prevent stain, calculus and plaque after a dental prophylaxis.
Methods: After IRB and consent, eligible adults with plaque and stain/calculus received a dental prophylaxis. After two weeks, baseline scores were used to randomly balance and assign subjects to daily oral hygiene with either 1) a 2-step system with 0.454% stannous fluoride dentifrice and 3% H2O2 gel (Crest® Pro-Health® [HD]™, Procter & Gamble) or 2) a 0.76% NaMFP dentifrice (Colgate® Cavity Protection, Colgate-Palmolive) control. Test products were dispensed blind to treatment in a kit with a regular soft brush and instructions for twice-daily at-home use for 10-weeks. Stain area and intensity (Lobene Index), mm of calculus (Volpe-Manhold Index) and plaque coverage (Rustogi Modification of the Navy Plaque Index) were measured before/after prophylaxis over a 12 week period along with clinical examinations to assess safety.
Results: 49 subjects enrolled (mean age = 40.4 years) and 48 completed the 12 week study. Overall baseline (pre-prophylaxis) means (SD) were 0.27 (0.36) for composite stain, 6.9 (4.8) for calculus, and 0.66 (0.05) for plaque. After 4-weeks assigned product use, groups differed significantly (p<0.01) on stain, calculus and plaque prevention, favoring the two-step group. After 10-weeks, only the two-step hygiene group showed no mean increase in stain compared to the immediate post-prophylaxis measures. In addition, stain, calculus and plaque accumulations were 73%, 59% and 31% lower in the two-step group versus control, with treatments differing (p≤0.0002) on all measures.
Conclusions: In a randomized controlled trial, use of a two-step 0.454% SnF2 then 3.0% H2O2 paste and gel sequence prevented stain, calculus and plaque accumulation after prophylaxis.
Methods: After IRB and consent, eligible adults with plaque and stain/calculus received a dental prophylaxis. After two weeks, baseline scores were used to randomly balance and assign subjects to daily oral hygiene with either 1) a 2-step system with 0.454% stannous fluoride dentifrice and 3% H2O2 gel (Crest® Pro-Health® [HD]™, Procter & Gamble) or 2) a 0.76% NaMFP dentifrice (Colgate® Cavity Protection, Colgate-Palmolive) control. Test products were dispensed blind to treatment in a kit with a regular soft brush and instructions for twice-daily at-home use for 10-weeks. Stain area and intensity (Lobene Index), mm of calculus (Volpe-Manhold Index) and plaque coverage (Rustogi Modification of the Navy Plaque Index) were measured before/after prophylaxis over a 12 week period along with clinical examinations to assess safety.
Results: 49 subjects enrolled (mean age = 40.4 years) and 48 completed the 12 week study. Overall baseline (pre-prophylaxis) means (SD) were 0.27 (0.36) for composite stain, 6.9 (4.8) for calculus, and 0.66 (0.05) for plaque. After 4-weeks assigned product use, groups differed significantly (p<0.01) on stain, calculus and plaque prevention, favoring the two-step group. After 10-weeks, only the two-step hygiene group showed no mean increase in stain compared to the immediate post-prophylaxis measures. In addition, stain, calculus and plaque accumulations were 73%, 59% and 31% lower in the two-step group versus control, with treatments differing (p≤0.0002) on all measures.
Conclusions: In a randomized controlled trial, use of a two-step 0.454% SnF2 then 3.0% H2O2 paste and gel sequence prevented stain, calculus and plaque accumulation after prophylaxis.