IADR Abstract Archives
Surgical Treatment of Peri-Implantitis Combined With Keratinized Mucosa Augmentation, a Dual-Centre RCT: 3-Year Results
Objectives: To evaluate the efficacy of a xenogeneic collagen matrix concomitant to the surgical treatment of peri-implantitis to augment the width of keratinized mucosa (KM) over 3 years.
Methods: In this 36-month parallel-arm randomized controlled clinical trial, patients with peri-implantitis were randomly assigned, one month after non-surgical therapy, to surgical resective treatment of peri-implantitis consisting on an apically positioned flap (APF) in combination with a KM augmentation procedure, either with an autologous free gingival graft (FGG) or a collagen matrix (CM). Primary outcomes were the increase in the width of KM and probing pocket depth (PPD) reduction at 36 months. As secondary outcomes, peri-implant radiographic and patient-reported outcomes were assessed.
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Results: Forty-one patients (20 in the CM group and 21 in the FGG group) completed the three-year follow-up. Disease resolution was 47.6% in the FGG group and 35.0% in the CM group, being these differences non-significant. PPDs were reduced by 1.4 mm [95% confidence interval (CI): 0.6, 2.2] and 1.5 mm (95% CI: 1.1, 1.9), respectively. However, the increase of KM was significantly higher in the APF+FGG compared with the APF+CM group (1.0 mm; 95% CI: 0.5, 1.5 versus 2.0 mm; 95% CI: 1.3, 2.7).
Conclusions: The tested surgical modalities resulted in similar improvements of the clinical parameters. Both FGG and CM increased the KM, but this gain was higher at the 36- months examination for the FGG.
Methods: In this 36-month parallel-arm randomized controlled clinical trial, patients with peri-implantitis were randomly assigned, one month after non-surgical therapy, to surgical resective treatment of peri-implantitis consisting on an apically positioned flap (APF) in combination with a KM augmentation procedure, either with an autologous free gingival graft (FGG) or a collagen matrix (CM). Primary outcomes were the increase in the width of KM and probing pocket depth (PPD) reduction at 36 months. As secondary outcomes, peri-implant radiographic and patient-reported outcomes were assessed.
[
Results: Forty-one patients (20 in the CM group and 21 in the FGG group) completed the three-year follow-up. Disease resolution was 47.6% in the FGG group and 35.0% in the CM group, being these differences non-significant. PPDs were reduced by 1.4 mm [95% confidence interval (CI): 0.6, 2.2] and 1.5 mm (95% CI: 1.1, 1.9), respectively. However, the increase of KM was significantly higher in the APF+FGG compared with the APF+CM group (1.0 mm; 95% CI: 0.5, 1.5 versus 2.0 mm; 95% CI: 1.3, 2.7).
Conclusions: The tested surgical modalities resulted in similar improvements of the clinical parameters. Both FGG and CM increased the KM, but this gain was higher at the 36- months examination for the FGG.