IADR Abstract Archives

Mechanical and Antimicrobial Behavior of Experimental Glasses on Translucent Zirconia

Objectives: Evaluate the mechanical, optical, and antimicrobial effects of experimental glasses applied on 5 mol% yttrium partially stabilized zirconia (5Y-PSZ).
Methods: Discs (ISO 6872, 12x1.2 mm), squares (4x4x1.6 mm), and zirconia abutments/crowns of 5Y-PSZ (UTML Katana Kuraray) were prepared. All the standard geometry specimens were sintered and divided into four groups: C (5Y-PSZ as sintered); G (5Y-PSZ+commercial glaze); SL (5Y-PSZ+boron-doped soda lime glass), and SLAg (5Y-PSZ+silver-doped soda-lime glass). One group of 5Y-PSZ abutments were tested as sintered (C), another coated with SL, and a third one with SLAg. Cytotoxicity (MTT assay), biaxial flexural strength (MPa), translucency (TP00), and roughness (Ra and Rz) tests were performed. Candida albicans (CA), Streptococcus sanguinis (SS), and Escherichia coli (EC) were collected between the abutment and implant after 7 days through the CFU test (n=8). Scanning electronic microscopy (SEM) was performed after the CFU test. Nine 5Y-PSZ crowns were cemented on their uncoated and coated counterpart abutments (n=3/group) and subjected to a step-stress fatigue test starting at 40 N, load steps of 10 N (100000 cycles each), at 15 Hz. Statistical analyses were performed to calculate the material’s modulus (m), and characteristic strength (σ0, 95% CI) for biaxial flexural strength. CFU, cytotoxicity, translucency and roughness data were analyzed by one-way ANOVA followed by Tukey’s HSD (α=0.05).
Results: Both glasses did not induce cytotoxic effects on the mesenchymal cells (P=0.59). TP00, m, and cycles to failure were similar for all groups. However, CFU, roughness, biaxial strength, and σ0 showed significant differences (p<0.05). The results are shown in the Table. SEM images showed a reduction in microorganisms amounts on SL surfaces. The failure mode per group was on the metallic abutment.
Conclusions: SL improved the biaxial strength of 5Y-PSZ zirconia, promoted antimicrobial effect, and showed cytocompatibility. Moreover, both SL and SLAg decreased the surface roughness, and did not affect 5Y-PSZ’s fatigue behavior and translucency.

2024 IADR/AADOCR/CADR General Session (New Orleans, Louisiana)
New Orleans, Louisiana
2024
0979
Dental Materials 1: Ceramic-based Materials
  • Silva, Ana Carolina  ( UNESP , São José dos Campos , SP , Brazil )
  • Marinho, Renata Marques De  ( UNESP , São José dos Campos , SP , Brazil )
  • Rodrigues, Camila  ( Federal University of Santa Maria , Santa Maria , Rio Grande do Sul , Brazil )
  • Sabino, Clarice  ( UNESP , São José dos Campos , SP , Brazil )
  • Silva, Juliana  ( UNESP , São José dos Campos , SP , Brazil )
  • Alves, Larissa  ( USP , Bauru , São Paulo , Brazil )
  • Campos, Tiago  ( USP , Bauru , São Paulo , Brazil )
  • Bonfante, Estevam  ( USP , Bauru , São Paulo , Brazil )
  • Marocho, Susana  ( University of Mississipi Medical Center , Jackson , Mississippi , United States )
  • Griggs, Jason  ( University of Mississipi Medical Center , Jackson , Mississippi , United States )
  • FAPESP (2023/03271-7 and 2021/03878-3)
    None
    Poster Session
    Biological Properties of Ceramics and Experimental Materials
    Thursday, 03/14/2024 , 03:45PM - 05:00PM
    CFU, cell viability, biaxial flexural strength (BFS), Weibull modulus (m), characteristic strength (σ0), cycles/load to failure, translucency, and roughness data
     CFU (SD)  Cell viability in % (SD)BFS means (SD)m
    (95% CI)
    σ0 (95% CI)Cycles/Load to failure (N)TP00 (SD)Roughness in µm (SD) 
    GroupsCASSEC      RaRz
    Control6.1 (0.2)A9.5 (0.5)A9.3 (0.6)A100.0 (0.1)A*******
    C5.2 (1.2)A7.6 (1.3)B7.5 (0.9)B79.3 (0.1)A351.0 (56.5)A6.6 (4.7-9.3)A375.1 (348.3 - 404.0)A628.070/ 106.6A13.4 (1.1)A0.361 (0.1)A4.028 (0.9)A
    G***85.8 (0.1)A453.8 (55.4)B11.2 (7.7-16.3)A475.8 (455.7 - 496.7)B*14.0 (0.6)A0.398 (0.1)A3.140 (1.4)A
    SL3.9 (0.4)B6.6 (0.8)C6.8 (0.5)C82.4 (0.1)A586.5 (60.0)C11.5 (8.0-16.6)A612.8 (587.5 - 639.2)C618.010/ 110.0A13.8 (1.6)A0.117 (0.07)B0.535 (0.4)B
    SLAg4.3 (0.3)A7.4 (0.3)BC7.1 (0.6)BC83.9 (0.04)A455.4 (83.7)B5.8 (4.1-8.2)A490.5 (450.7 - 533.8)B625.650/ 113.3A14.0 (0.88)A0.182 (0.1)B1.601 (1.0)C
    *Means that do not share the same letter are significantly different (Tukey’s test, p ≤ 0.05).