IADR Abstract Archives
Dental Outcomes and Medication use in Young Adults
Objectives: To investigate the association between medication use and dental outcomes in 2,585 individuals aged between 18 and 44 years.
Methods: Medical and dental data were obtained from the University of Pittsburgh Dental Registry and DNA Repository project. Demographic data (sex, ethnicity, and age), medical history, and oral health were collected. Self-reported drug use was obtained for psychiatric or neurological disorders, immunomodulators, pain, antimicrobials, proton pump inhibitors, vitamins and supplements, cardiovascular disease, drugs for birth control, and other medications. Dental outcomes (sound, caries experience, caries activity, periodontal diseases, endodontic treatment, and missing or extracted teeth) were considered for teeth 2, 4, 6, 8, 18, 20, 22, and 24 (Universal Numbering System). Data were analyzed by inferential statistics and a 95% confidence level.
Results: The use of some type of drug is identified for 51.66% (n=1,336) of the sample, with higher frequencies for drugs for psychiatric/neurological disorders (18.25%, n=472), drugs for birth control (12.03%, n=311) and pain medications (10.87%, n=281). In general, the use of these drugs was associated (p<0.0001) with a lower number of sound teeth and a higher number of extracted teeth, for all types of teeth evaluated. However, the use of drugs for birth control was associated with a greater number of healthy teeth for all teeth studied (p<0.0001). Drug use is also associated with a greater number of maxillary and maxillary teeth affected by dental caries, and the use of drugs for birth control is related to a lower number of active caries in these same groups of teeth (p<0 .0001).
Conclusions: The use of drugs for psychiatric or neurological disorders, immunomodulators, pain, antimicrobials, proton pump inhibitors, and cardiovascular disease is associated with fewer healthy teeth, more extracted or missing teeth, and more active caries in anterior teeth. The use of birth control drugs is associated with better dental health conditions.
Methods: Medical and dental data were obtained from the University of Pittsburgh Dental Registry and DNA Repository project. Demographic data (sex, ethnicity, and age), medical history, and oral health were collected. Self-reported drug use was obtained for psychiatric or neurological disorders, immunomodulators, pain, antimicrobials, proton pump inhibitors, vitamins and supplements, cardiovascular disease, drugs for birth control, and other medications. Dental outcomes (sound, caries experience, caries activity, periodontal diseases, endodontic treatment, and missing or extracted teeth) were considered for teeth 2, 4, 6, 8, 18, 20, 22, and 24 (Universal Numbering System). Data were analyzed by inferential statistics and a 95% confidence level.
Results: The use of some type of drug is identified for 51.66% (n=1,336) of the sample, with higher frequencies for drugs for psychiatric/neurological disorders (18.25%, n=472), drugs for birth control (12.03%, n=311) and pain medications (10.87%, n=281). In general, the use of these drugs was associated (p<0.0001) with a lower number of sound teeth and a higher number of extracted teeth, for all types of teeth evaluated. However, the use of drugs for birth control was associated with a greater number of healthy teeth for all teeth studied (p<0.0001). Drug use is also associated with a greater number of maxillary and maxillary teeth affected by dental caries, and the use of drugs for birth control is related to a lower number of active caries in these same groups of teeth (p<0 .0001).
Conclusions: The use of drugs for psychiatric or neurological disorders, immunomodulators, pain, antimicrobials, proton pump inhibitors, and cardiovascular disease is associated with fewer healthy teeth, more extracted or missing teeth, and more active caries in anterior teeth. The use of birth control drugs is associated with better dental health conditions.