Caries-OUT Study: Feasibility, Acceptability and Efficacy During the Pandemic
Objectives: Caries OUT derived from an RCT suspended at the pandemic start, as a 1-year caries-control multicentre single-group study in children, using the risk-based patient-centred, preventive and tooth-preserving CariesCare International (CCI) caries-management system, adapted for the pandemic (non-aerosol-generating procedures -non-AGP- and reduced on-site appointments). This study aimed to describe the feasibility, acceptability and efficacy of running CariesOUT during the pandemic. Methods: Caries OUT IRB amendment: June-2020. Same 21 centres were invited (Latin-America: n=13; North-America: n=3; Europe n=5; children/centre: n=27). Feasibility included number of centres and individuals recruited/year quarter-Q (baseline-T0), and drop-outs (5-month follow-up-T1); Dentists/Parents’ Acceptability of CCI-adapted (Treatment-Evaluation-Inventory -TEI- questionnaire) at T1, and Efficacy: children’s caries-risk control and oral-health behaviours’ improvement (final 1-year follow-up: T2). Results: By July-2020, all centres agreed to participate, receiving online training in CCI-adapted during September (3 dentists/centre). Starting Q: Q4-2020. Feasibility: By Q4-2021, 15 centres (71.4%) have started/finished T0 (Latin-America: 13; Europe: 2); in Q4-2020: 3, 2021-Q1: 3, 2021-Q2: 6, 2021-Q3: 1, 2021-Q4: 2. n=346 children (85.4%) have been recruited (T0) (56.3% girls; mean age: 5.7±1.6y), distributed by Q in: Q4-2020: n=51 (14.7%); in 2021: Q1-n=69 (19.9%), Q2-n=102 (29.5%), Q3-n=72 (20.8%), Q4-n=52 (15.0%). Drop-out: 6.4%. Acceptability (T1 by Q4-2022): 13 centres, n=247 children. TEI questionnaires returned: parents (n=73, 29.6%); dentists (n=20, 51.3%) reporting: additional caries-risk and oral-health knowledge (dentists: 72.6%; parents: 65.0%); appropriate toothbrushing practice improvement (dentists: 60.0%; parents: 80.8%); appropriate sugar-intake control (dentists: 50.0%; parents: 76.7%); high acceptance of non-AGPs (dentists: 85.0%; parents: 87.7%) and CCI (dentists: 75.0%; parents: 84.9%). Efficacy (T2, n=44): significant reductions (p<0.05) in children with high-caries risk (T0: 98.0%, T2: 22.7%) and very-inadequate oral-health behaviours (T0: 54.9%, T2: 0%). Conclusions: Under the pandemic challenge, Caries OUT has been feasible, accepted by dentist/parents, and efficacious.
Division: Meeting:2022 IADR/APR General Session (Virtual) Location: Year: 2022 Final Presentation ID:1109 Abstract Category|Abstract Category(s):Cariology Research-Clinical & Epidemiological Studies
Authors
Martignon, Stefania
( Universidad El Bosque
, Bogota
, D.C.
, Colombia
)
Abreu Placeres, Ninoska
( Universidad Iberoamericana
, Santo Domingo
, Distrito Nacional
, Dominican Republic
)
Bonifácio, Clarisa
( Academic Centre for Dentistry Amsterdam (ACTA)
, Amsterdam
, Netherlands
)
Braga, Mariana
( University of Sao Paulo
, Sao Paulo
, Brazil
)
Carletto-körber, Fabiana
( Universityersidad Nacional De Cordoba
, Valle Hermoso
, Argentina
)