IADR Abstract Archives
Osteoradionecrosis Risk on Irradiated Head and Neck Cancer Patients: Electronic Dental Records Study
Objectives: Over the last two decades, investigations have demonstrated a decreased trend in the likelihood of osteoradionecrosis of the jaw (ORNJ) after extraction. The aim of this study was to explore into the data quality and potential risk factors for ORNJ in irradiated head and neck cancer patients' electronic dental records (EDRs).
Methods: Patients diagnosed with head and neck cancer who had irradiation between January 2010 and December 2020 were included in this retrospective cohort analysis. Patient charts showing evidence of "head and neck cancer," "oral cancer," "radiotherapy," "radiation," and "oral complication" were identified by an Informatics Analyst querying the EDR. Subsequently, the charts were manually reviewed, and data quality were assessed on three dimensions: completeness, accuracy, and consistency in this study. The patient, tumor, systemic condition/drug, oral condition, treatment/trauma, and radiation were all categorized as potential risk factors.
Results: 359 patients were included. With the exception of radiation- related factors, we found that the data quality was generally sufficient to support the research. Multivariate logistic regression analysis demonstrated that smoking (OR, 9.0; 95% CI, 1.9–43.0; P = 0.006), steroid use (OR, 6.4; 95% CI, 1.3-30.8; P = 0.021), oral health status (OR, 23.7; 95% CI, 2.7–211.0; P = 0.005), and post-irradiation extraction (OR, 3.8; 95% CI, 1.0–14.4; P = 0.050) emerged as significant factors in predicting the occurrence of ORNJ development on irradiated head and neck cancer patients.
Conclusions: A ten-year retrospective analysis of data from an EDR revealed that smoking, steroid use, poor oral status, and post-irradiation extraction are all factors linked to an increased risk of developing ORNJ. The quality of EDR data may be systematically assessed by determining the completeness, accuracy, and consistency of the underlying data. Radiation-related factors, in particular, were poorly documented, highlighting the need for collecting or incorporating this information into the EDR.
Methods: Patients diagnosed with head and neck cancer who had irradiation between January 2010 and December 2020 were included in this retrospective cohort analysis. Patient charts showing evidence of "head and neck cancer," "oral cancer," "radiotherapy," "radiation," and "oral complication" were identified by an Informatics Analyst querying the EDR. Subsequently, the charts were manually reviewed, and data quality were assessed on three dimensions: completeness, accuracy, and consistency in this study. The patient, tumor, systemic condition/drug, oral condition, treatment/trauma, and radiation were all categorized as potential risk factors.
Results: 359 patients were included. With the exception of radiation- related factors, we found that the data quality was generally sufficient to support the research. Multivariate logistic regression analysis demonstrated that smoking (OR, 9.0; 95% CI, 1.9–43.0; P = 0.006), steroid use (OR, 6.4; 95% CI, 1.3-30.8; P = 0.021), oral health status (OR, 23.7; 95% CI, 2.7–211.0; P = 0.005), and post-irradiation extraction (OR, 3.8; 95% CI, 1.0–14.4; P = 0.050) emerged as significant factors in predicting the occurrence of ORNJ development on irradiated head and neck cancer patients.
Conclusions: A ten-year retrospective analysis of data from an EDR revealed that smoking, steroid use, poor oral status, and post-irradiation extraction are all factors linked to an increased risk of developing ORNJ. The quality of EDR data may be systematically assessed by determining the completeness, accuracy, and consistency of the underlying data. Radiation-related factors, in particular, were poorly documented, highlighting the need for collecting or incorporating this information into the EDR.