IADR Abstract Archives
Association Between Lipid Metabolism and Periodontitis in Obese Patients: a Cross-Sectional Study
Objectives: To investigate the clinical parameters of periodontitis, serum lipid metabolism and adipokines level in patients with obesity and periodontitis and their correlations.
Methods: A total of 112 patients admitted to Xi’an Jiaotong University College of Stomatology were included in this study. They were divided into normal body weight group (BMI≤25, n=36), overweight group (2530, n=38). The diagnosis of periodontitis was based on the newest international classification of periodontitis. The general information and clinical periodontal measurements of 6 exponent teeth of the patients were recorded. Serum and gingival crevicular fluid samples were collected and the related indexes in serum and gingival crevicular fluid were determined by ELISA or other biochemical analysis.
Results: Under the condition of similar distribution of periodontitis in each group, the depth of periodontal pocket, the level of attachment loss and the inflammatory cytokines in gingival crevicular fluid in obesity group and overweight group were higher than those in normal body weight group. The body mass index (BMI) and waist-to-hip ratio (WHR) were significantly positively correlated with the depth of periodontal exploration and the level of attachment loss. Serum levels of triglyceride, cholesterol, low density lipoprotein and adipokine visfatin, leptin and resistin were significantly correlated with the degree of periodontitis.
Conclusions: The progression of obesity is positively with the aggravation of periodontitis. Obesity may aggravate the damage to periodontal tissue by regulating the secretion level of adipokines.
Methods: A total of 112 patients admitted to Xi’an Jiaotong University College of Stomatology were included in this study. They were divided into normal body weight group (BMI≤25, n=36), overweight group (25
Results: Under the condition of similar distribution of periodontitis in each group, the depth of periodontal pocket, the level of attachment loss and the inflammatory cytokines in gingival crevicular fluid in obesity group and overweight group were higher than those in normal body weight group. The body mass index (BMI) and waist-to-hip ratio (WHR) were significantly positively correlated with the depth of periodontal exploration and the level of attachment loss. Serum levels of triglyceride, cholesterol, low density lipoprotein and adipokine visfatin, leptin and resistin were significantly correlated with the degree of periodontitis.
Conclusions: The progression of obesity is positively with the aggravation of periodontitis. Obesity may aggravate the damage to periodontal tissue by regulating the secretion level of adipokines.