Radiomorphometric and Densitometric Assessment of Mandibular Bone Density
Objectives: To evaluate the association between optical density (OD) and mandibular bone mineral density (BMD) measurements in panoramic radiographs.
Methods: A total of 462 randomly selected anonymised panoramic radiographs of female (n=231) and male (n=231) patients treated in Zalgiris Clinic of Vilnius University Hospital, aged 50-90, mean age 62 (SD=9.3) years, were analysed by a single calibrated operator (DK) between February 2021 and June 2021. The representative sample size was calculated based on the prevalence of osteoporosis in Lithuania. Using an image analysis software, the OD of the mandibular cortex was measured in a specific standardised area in the gonial angle of the mandible and below the mental foramen. The mandibular BMD was evaluated using mental index (MI), mandibular cortical index (MCI) and gonial index (GI). Statistical analysis of the data was performed using independent samples Student’s t-test and Pearson’s correlation coefficient. Statistical significance was set at p<0.05. The study protocol was approved by the Vilnius Regional Biomedical Research Ethics Committee.
Results: The mean of OD, MI, MCI, and GI, were observed significantly higher in males than in females (p=0.045, p=0.036, p=0.032, p=0.039, respectively). There were moderate significant correlations between OD and MI in males and females (r=0.533, p=0.031; r=0.529, p=0.027, respectively), OD and MCI in males and females (r=-0.621, p=0.041; r=-0.655, p=0.038, respectively) and OD and GI in males (r=0.324, p=0.037). Moreover, there was a weak significant correlation between OD and GI in females (r=0.277, p=0.031).
Conclusions: In the population studied OD may be associated with the mandibular BMD.