IADR Abstract Archives
Effectiveness of Self-Assembling Peptide11_4 on Color Masking of White-Spot-Lesions
Objectives: Masking the color of white-spot–lesions (WSLs) is a big goal to achieve in esthetic dentistry. The efficiency of any remineralizing agent to mask the white scar depends on its ability to diffuse deep into the lesion. Remineralization of WSL results in a decreased amount of light scattering and therefore, an increase in translucency. This study aims to compare the effectiveness of MI paste (CaseinPhosphopeptide-AmorphousCalciumPhosphate), and Curodont Repair Fluoride Plus (self-assembling-peptide), at improving the light reflectivity and consequently appearance of WSLs using spectrophotometric analysis.
Methods: Treatment windows of 2 mm x 3 mm were created in 30 extracted human-molars using acid resistant nail polish. To create WSL, teeth were exposed to a demineralization solution for 14-days in water-shaker bath at 37° with constant agitation. Specimens were randomly assigned to two groups; Curodont (CF) and MI paste (MI). Following treatment, groups were exposed to pH-cycle (4-hours demineralization, 20-remineralization) for 27 days. Spectrophotometer was used to quantitatively measure enamel-lightness values (L*) of each sample at 3-time points; before treatment (T0), after WSL (T1), post-treatment and pH-cycle (T2). Lightness-change (ΔL) was analyzed to the changes from pre-treatment to post-treatment
Results: Between-groups, Two Sample T-Test showed no statistically significant difference in the L* value at each time point (p<0.05). Within each group, repeated-measure ANOVA showed statistically significant decrease in L* from T0 to T1 combined with chalky-white visual-appearance of the specimens were two pre-defined criteria for successful WSL creation. Also, there was no statistically significant difference for the change in L* values (ΔL) that occurred between T1-T2 within each group.
Conclusions: Within the limitations of this study, Curodont Repair Fluoride Plus and MI paste treatments were not able to restore enamel lightness and translucency. The L* increased after treatment at T2 (post-treatment), but not to the level of T0 (before treatment).
Methods: Treatment windows of 2 mm x 3 mm were created in 30 extracted human-molars using acid resistant nail polish. To create WSL, teeth were exposed to a demineralization solution for 14-days in water-shaker bath at 37° with constant agitation. Specimens were randomly assigned to two groups; Curodont (CF) and MI paste (MI). Following treatment, groups were exposed to pH-cycle (4-hours demineralization, 20-remineralization) for 27 days. Spectrophotometer was used to quantitatively measure enamel-lightness values (L*) of each sample at 3-time points; before treatment (T0), after WSL (T1), post-treatment and pH-cycle (T2). Lightness-change (ΔL) was analyzed to the changes from pre-treatment to post-treatment
Results: Between-groups, Two Sample T-Test showed no statistically significant difference in the L* value at each time point (p<0.05). Within each group, repeated-measure ANOVA showed statistically significant decrease in L* from T0 to T1 combined with chalky-white visual-appearance of the specimens were two pre-defined criteria for successful WSL creation. Also, there was no statistically significant difference for the change in L* values (ΔL) that occurred between T1-T2 within each group.
Conclusions: Within the limitations of this study, Curodont Repair Fluoride Plus and MI paste treatments were not able to restore enamel lightness and translucency. The L* increased after treatment at T2 (post-treatment), but not to the level of T0 (before treatment).
