Distraction Osteogenesis Maxillary Expansion for Treatment of OSA: Systematic Review
Objectives: To systematically assess and examine the efficacy of Distraction Osteogenesis Maxillary Expansion (DOME) as a successful treatment option for adult patients with Obstructive Sleep Apnea (OSA). Methods: A detailed search was performed on online databases including PubMed, Embase, Medline, and Elsevier as well as offline database, Parnassus UCSF Library. Key words for search included: Distraction Osteogenesis Maxillary Expansion, Maxillary Transverse Distraction Osteogenesis, Surgically Assisted Rapid Maxillary Expansion, and Obstructive Sleep Apnea.
Inclusion criteria for this review: (1) Population: adult (18 years or older) patients with OSA (2) Intervention: isolated maxillary expansion (3) Comparison: pre- and post- maxillary expansion (4) Outcome: general outcomes including but not limited to polysomnographic data, Apnea-Hypopnea Index (AHI), Lowest Oxygen Saturation score (LSAT), and quality of life. (5) Study design: All published studies in all languages. Exclusion criteria for this review: (1) Descriptive articles or editorials (2) Studies with qualitative outcomes only (3) Studies with other treatment options included such as tonsillectomy (4) Studies with patient whose BMI score changed significantly (20% or greater) during the course of the treatment (due to confounding problems) Results: A total of 116 papers were reviewed from the initial search. Upon examination using the inclusion and exclusion criteria, 10 papers were selected for this review. Maxillary expansion was measured with inter-tooth distance such as intercuspid, interbicuspid, or intermolar distance. The outcomes were measured using polysomnographic data, minimum oxygen saturation rate, arousal index, AHI score, and other outcomes. Studies have revealed that AHI and LSAT scores have improved for more than 90% of the study participants. Conclusions: Distraction Osteogenesis Maxillary Expansion appears to be a promising treatment option for adult patients with OSA. Further studies with randomized controlled trials and long term follow up studies are encouraged.
IADR/AADR/CADR General Session
2020 IADR/AADR/CADR General Session (Washington, D.C., USA) Washington, D.C., USA
2020 1514 Orthodontics Research
Jang, Esther
( UCSF
, San Francisco
, California
, United States
)