IADR Abstract Archives
Effect of Oversized Implant Site Preparation on Osseointegration In vivo
Objectives: The aim of this study was to evaluate the effect of oversized surgical preparation of the implant recipient site on a) marginal peri-implant bone level (MBL) and b) histomorphometrical parameters of osseointegration, in an animal platform with dense bone.
Methods: Ten hydrophilic tapered implants (11.5 mm x 3.5 mm, L x Ø) with a progressive thread geometry and a hydrophilic surface were inserted in the edentulous mandible of mixed-breed female minipigs, following either a standard [SD, control] vs. oversized [OD, test] drilling protocol (n = 5/group). SD included a 3-step series of drills without profiling of the cortical bone (implant-last drill discrepancy [IDD] = 0.3 mm). OD included a 5-step series of drills and profiling of the cortical bone which resulted, respectively, in two IDD along the implant axis: (1) IDD = 0.0 mm in the 3.5-mm coronal aspect of the implant; ad (2) IDD = 0.1 mm in the middle and apical aspect of the implant. Maximum insertion torque values (ITV; N.cm) were recorded and non-submerged healing was allowed for 12 weeks. Following termination, mandibular blocks were harvested for non-decalcified histomorphometric evaluation.
Results: OD produced statistically significant lower ITV (22.00 ± 2.73 N.cm vs. 51.25 ± 7.50 N.cm, P < 0.05) and it showed reduced marginal bone changes (3.38 ± 2.09 mm), however without significant differences when compared to SD (5.56 ± 4.53 mm). In contrast, OD showed statistically significant higher values of bone-to-implant (BIC: 26.92 ± 5.85%) and peri-implant bone density (BD: 39.18 ± 16.95%) compared to SD (BIC: 8.79 ± 7.78%, P < 0.01; BD: 10.23 ± 11.18%, P < 0.05).
Conclusions: Oversized surgical preparation of the implant site a) yielded low insertion torque of a tapered implant presenting a hydrophilic surface technology, b) preserved better the MBL and c) enhanced osseointegration and peri-implant bone density, compared with standard drilling.
Methods: Ten hydrophilic tapered implants (11.5 mm x 3.5 mm, L x Ø) with a progressive thread geometry and a hydrophilic surface were inserted in the edentulous mandible of mixed-breed female minipigs, following either a standard [SD, control] vs. oversized [OD, test] drilling protocol (n = 5/group). SD included a 3-step series of drills without profiling of the cortical bone (implant-last drill discrepancy [IDD] = 0.3 mm). OD included a 5-step series of drills and profiling of the cortical bone which resulted, respectively, in two IDD along the implant axis: (1) IDD = 0.0 mm in the 3.5-mm coronal aspect of the implant; ad (2) IDD = 0.1 mm in the middle and apical aspect of the implant. Maximum insertion torque values (ITV; N.cm) were recorded and non-submerged healing was allowed for 12 weeks. Following termination, mandibular blocks were harvested for non-decalcified histomorphometric evaluation.
Results: OD produced statistically significant lower ITV (22.00 ± 2.73 N.cm vs. 51.25 ± 7.50 N.cm, P < 0.05) and it showed reduced marginal bone changes (3.38 ± 2.09 mm), however without significant differences when compared to SD (5.56 ± 4.53 mm). In contrast, OD showed statistically significant higher values of bone-to-implant (BIC: 26.92 ± 5.85%) and peri-implant bone density (BD: 39.18 ± 16.95%) compared to SD (BIC: 8.79 ± 7.78%, P < 0.01; BD: 10.23 ± 11.18%, P < 0.05).
Conclusions: Oversized surgical preparation of the implant site a) yielded low insertion torque of a tapered implant presenting a hydrophilic surface technology, b) preserved better the MBL and c) enhanced osseointegration and peri-implant bone density, compared with standard drilling.
