IADR Abstract Archives
Exploring Affection Patterns of Molar Hypomineralization Defects
Objectives: The aims of the study were to test if affection patterns of molar hypomineralization are symmetric between arches and sides of the mouth; whether the number of affected first permanent molars (FPMs) and second primary molars (SPMs) were associated with the involvement of other teeth and compare the presence, location, severity and color of lesions to clinical situation.
Methods: Thirty-five patients aged 3-14 (9.00 ± 3.32) years, having at least one hypomineralized FPM or SPM were evaluated. All erupted teeth (n=845) were scored according to the European Academy of Pediatric Dentistry criteria. Chi square, Fisher’s exact, Student’s t and Pearson correlation tests were used (p<0.01).
Results: Twenty-eight (80%) of the patients showed hypomineralized teeth both in the upper and lower arches (p<0.01), while 32 (91.4%) showed affected teeth on both sides of the mouth (p<0.01). Mean number of affected teeth in patients showing any severe hypomineralized FPM or SPM (5.63 ± 2.83) was significantly higher (p<0.01) than in patients showing mild hypomineralization in these elements (2.62 ± 0.92). Distribution of the number of affected surfaces, color and severity on the affected teeth did not show symmetry. Yellow-brown opacities in posterior teeth were significantly related to the presence of post eruptive breakdown (PEB) (p<0.01). Moreover, presence of hypomineralization signs on regions of masticatory effort showed a positive correlation with the presence of caries lesions, restorations or PEB (p=0.0014).
Conclusions: Although presence of hypomineralization signs was symmetric between arches and sides of the mouth, specific phenotypes including lesion color, severity and number of surfaces affected were not. The higher the number of affected surfaces in FPMs or SPMs, the higher were the chance of hypomineralization in primary and permanent canines. This evidence supports a complex genetic-type of inheritance for hypomineralization defects, with variable expressivity and distinct prevalence in different populations.
Methods: Thirty-five patients aged 3-14 (9.00 ± 3.32) years, having at least one hypomineralized FPM or SPM were evaluated. All erupted teeth (n=845) were scored according to the European Academy of Pediatric Dentistry criteria. Chi square, Fisher’s exact, Student’s t and Pearson correlation tests were used (p<0.01).
Results: Twenty-eight (80%) of the patients showed hypomineralized teeth both in the upper and lower arches (p<0.01), while 32 (91.4%) showed affected teeth on both sides of the mouth (p<0.01). Mean number of affected teeth in patients showing any severe hypomineralized FPM or SPM (5.63 ± 2.83) was significantly higher (p<0.01) than in patients showing mild hypomineralization in these elements (2.62 ± 0.92). Distribution of the number of affected surfaces, color and severity on the affected teeth did not show symmetry. Yellow-brown opacities in posterior teeth were significantly related to the presence of post eruptive breakdown (PEB) (p<0.01). Moreover, presence of hypomineralization signs on regions of masticatory effort showed a positive correlation with the presence of caries lesions, restorations or PEB (p=0.0014).
Conclusions: Although presence of hypomineralization signs was symmetric between arches and sides of the mouth, specific phenotypes including lesion color, severity and number of surfaces affected were not. The higher the number of affected surfaces in FPMs or SPMs, the higher were the chance of hypomineralization in primary and permanent canines. This evidence supports a complex genetic-type of inheritance for hypomineralization defects, with variable expressivity and distinct prevalence in different populations.
