IADR Abstract Archives

Evaluation of a New Antimicrobial Oral-aid in Oral Biofilm

The search for a therapeutic device that may be applied in wounds and oral mucosa lesion is a challenge for the Dentistry. A biodegradable oral-aid, made by chitosan and that liberates medicines has been developed in the will of fulfilling this necessity. An oral-aid that is biocompatible, bioavailable, biodegradable, with low cost and with antimicrobial action may has its use indicated to other health segments. In this study, we incorporated chlorhexidine, an efficient antimicrobial in the treatment of ulcerated lesions, trauma and surgical wounds.

Objectives: to analyse the action action of the banding in the total culture of oral biofil microoganisms.

Methods: Petri plaques containing Agar Mueller Hinton as culture medium had been previously prepared. Over the culture medium it was spread a broth containing microorganisms from a total oral biofilm and the bandings had been put over this culture. Different chlorhexidine concentrations were incorporated to the oral-aids: 0.1% (Group I); 0.5% (Group II); 1% (Group III) and 2% (Group IV). The plaques were included in anaerobiosis and in incubator with mean temperature of 37º for 48 hours. After the incubation period, the plaques were analyzed and the data was submitted to statistics analysis by ANOVA test.

Results: It could be observed the formation of inhibition halos of different sizes. Both Groups III and IV had inhibition halos statistically larger than Groups I and II. There is no statistically significant difference between the mean scores of the inhibition halos formed by the Groups I and II. This is also observed between the Groups III and IV.

Conclusions: the antimicrobial oral-aids are able to minimize the infectious process. The best dose X response relation was found with 1% chlorhexidine incorporated.

Division: IADR/LAR General Session
Meeting: 2012 IADR/LAR General Session (Iguaçu Falls, Brazil)
Location: Iguaçu Falls, Brazil
Year: 2012
Final Presentation ID: 1044
Abstract Category|Abstract Category(s): Dental Materials 5: Biocompatibility and Biologic Effects
Authors
  • Barbério, Gabriel  ( Bauru School of Dentistry - University of São Paulo, Bauru-SP, N/A, Brazil )
  • Mello, T.  ( Bauru School of Dentistry - University of São Paulo, Bauru-SP, N/A, Brazil )
  • Costa, S.  ( Bauru School of Dentistry - University of São Paulo, Bauru-SP, N/A, Brazil )
  • Oliveira, T.  ( Bauru School of Dentistry - University of São Paulo, Bauru-SP, N/A, Brazil )
  • Silva, M.  ( Bauru School of Dentistry - University of São Paulo, Bauru-SP, N/A, Brazil )
  • Silva, A.  ( Bauru School of Dentistry - University of São Paulo, Bauru-SP, N/A, Brazil )
  • Oliveira, R.  ( Bauru School of Dentistry - University of São Paulo, Bauru-SP, N/A, Brazil )
  • Costa, S.  ( School of Human Sciences and Arts - University of São Paulo, Sao Paulo-SP, N/A, Brazil )
  • Machado, M.  ( Bauru School of Dentistry - University of São Paulo, Bauru-SP, N/A, Brazil )
  • SESSION INFORMATION
    Poster Session
    Biocompatibility and Biologic Effects III
    06/21/2012