IADR Abstract Archives

Relationship between Periodontal Disease and Oxidative Stress in Cambodian Population

Objective: In rural area of developing countries, it is considered that increasing oxidative stress can be one of cause of progressive aging phenomenon and decreasing life expectancy. There is a possibility that periodontal disease is one of the risk factor to break out of oxidative stress. The purpose of this study is to improve the influence of oxidative stress associated with periodontitis in human body at rural area in Cambodia.

Method: Total numbers of subjects were 87 adults (38 male, 49 females, mean age 36.7±14.3) in Mondulkiri province located in the northeastern area of Cambodia. The basic information was charted according to sex, birth date, occupation, height, weight, BMI, blood pressure, pulse and interviewed life condition and anamnestic history. The oral condition was charted according to DMFT index, proving depth, BOP and mucosal disease. The level of oxidative stress was evaluated by d-ROMs test.

Result: Mean d-ROMs was 336.9±60.0 U.CARR. About 80 % of subjects obtain over 300 U.CARR. Mean DMFT index was 9.5±7.8 (Missing tooth: 6.0±58.7, Decayed tooth: 3.2±6.0, Filled tooth: 0.3±0.9). 25.3% (n=22) of subjects obtain under 3mm of proving depth, 44.8% (n=39) of subject obtain 4mm to 5mm of proving depth and 29.9% (n=26) obtain over 6mm of proving depth. Mean rate of BOP was 52.2%. d-ROMs level were correlated with age (r=0.23), DFMT index (r=0.30), missing tooth index (r=0.24), maximum proving depth (r=0.35), rate of BOP (r=0.43). ANOVA analysis was used the difference of d-ROMs and Group of Proving depth, and showed significantly difference.

Conclusion: This study is shown the possibility that periodontitis is cause of increasing oxidative stress. And increasing oxidative stress is possibly to damage to any organ of human body and accelerates aging.

Division: IADR/LAR General Session
Meeting: 2012 IADR/LAR General Session (Iguaçu Falls, Brazil)
Location: Iguaçu Falls, Brazil
Year: 2012
Final Presentation ID: 1582
Abstract Category|Abstract Category(s): Periodontal Research - Diagnosis / Epidemiology
Authors
  • Yano, Gen  ( Nihon University, Matsudo, Chiba, N/A, Japan )
  • Uy, Sophorn  ( University of Health Sciences, Phnom Penh, N/A, Cambodia )
  • Vorn, Vutha  ( University of Health Sciences, Phnom Penh, N/A, Cambodia )
  • Sok, Chea  ( University of Health Sciences, Phnom Penh, N/A, Cambodia )
  • Im, Puthavy  ( University of Health Sciences, Phnom Penh, N/A, Cambodia )
  • Miyata, Takahshi  ( Organization of International Support for Dental Education, Tokyo, N/A, Japan )
  • Akimoto, Yoshiaki  ( Nihon University, Matsudo, Chiba, N/A, Japan )
  • SESSION INFORMATION
    Poster Session
    Etiology and Pathogenesis of Periodontal Diseases
    06/21/2012