IADR Abstract Archives

Effects Of Probiotic On Candida Presence In Elderly

Objective: This study evaluated whether the consumption of the probiotic Yakult LB® (Lactobacillus casei and Bifidobacterium breve) was able to influence on the specific immunological response against Candida and on the presence of these yeasts in the oral cavity of healthy elderly individuals.

Method: Saliva samples of 42 volunteers were collected before and after the use of probiotic for 30 days, three times in week. The samples were plated in Dextrose Saboraud Agar with chloramphenicol, the colony-forming units (CFU/mL) were counted and the species of Candida were identified. Anti-Candida IgA analysis was conducted using the ELISA technique.

Result: It was verified a reduction in Candida prevalence (from 88.1% to 78.6%), in CFU/mL counts of Candida (p=0,01) and in numbers of non-albicans species, after the consumption of the probiotic. Immunological analysis demonstrated a significant increase in anti-Candida IgA levels (p=0,066).

Conclusion: The probiotic consumption reduced the amount of Candida in oral cavity of elderly and increased specific secretory immune response against these yeasts, suggesting its possible use in controlling oral candidosis and promoting health among these individuals.

Division: IADR/LAR General Session
Meeting: 2012 IADR/LAR General Session (Iguaçu Falls, Brazil)
Location: Iguaçu Falls, Brazil
Year: 2012
Final Presentation ID: 1548
Abstract Category|Abstract Category(s): Microbiology / Immunology
Authors
  • Leão, Mariella  ( University of Taubaté and Universidade Est. Paulista Julio Mesquita, Sao José dos Campos, N/A, Brazil )
  • Santos, Silvana  ( University of Taubaté, Taubaté, N/A, Brazil )
  • Silva, Célia Regina G  ( University of Taubaté, Taubaté, N/A, Brazil )
  • Faria, Ivan Da Silva  ( University of Taubaté, Taubaté, N/A, Brazil )
  • Jorge, Antonio Olavo Cardoso  ( Universidade Est. Paulista Julio Mesquita, Sao José dos Campos, N/A, Brazil )
  • SESSION INFORMATION
    Poster Session
    Candida II
    06/21/2012