Method: By means of a systematic review, the effectiveness and effect on some physicochemical properties of different disinfection means on extracted human teeth were compared.
Result: It seems that glutaraldehyde at 2 or 5.25% does not induce morphological changes. The autoclave used at 121 ° C increases microfiltration because the pressure and heat affect the collagen-hydroxyapatite ionic bonds. Aqueous Cloramine-T at 1% reduces the risk of transferring infection, has no adverse effects on collagen, keeps similar properties to those that the tooth has when freshly extracted, and does not affect the microleakage of dentin. Gamma radiation increases the elastic modulus; it does not change the dentinal permeability but induces the change of color in enamel. Thymol at 0.1% disinfects well; it does not affect the properties of the tooth and reduces the effects of demineralization by acids. Formalin at 10% preserves proteins, glycoproteins and polysaccharides of dental tissue; however, it is a potentially carcinogenic hazardous material. Sodium hypochlorite at 5.25% increases the porosity of the enamel, it modifies dentin protein matrix, so it is not advisable in dental research.
Conclusion: According to the systematic review, Cloramine-T at 1% concentration in water is considered the most effective means of disinfection in extracted human teeth due to the fact that it does not have any reported adverse effects on the structure of dental enamel or on the dentin collagen and proteins. It is also effective because it reduces the risk of transmitting infections.