IADR Abstract Archives

Determination of Remineralization of Apacider® Varnish on Human Dental Enamel

Objective: The purpose of this study was to determine the remineralization potential of Apacider® varnish on white spot lesion of human enamel.

Methods: The enamel discs (3 mm thickness) were prepared from buccal and lingual surface of human third molars and polished on the enamel surface to derive for flat testing area of 3x3 mm. An artificial caries were induced to the test area using pH cycling methods (Kumar et al, 2009).  Disks were randomly divided into 4 groups to be surface treated as follows: group 1) no treatment, group 2) applied with fluoride varnish using Duraphat® (Colgate) for 3 minutes in the first day, group 3) applied with Apacider® varnish for 3 min/week , and group 4) daily applied with CPP-ACP using Tooth mousse® (GC) for 3 min. They were treated for 4 weeks and stored in artificial saliva at 37oC for 30 days. Laser fluorescence measurements were performed before, after induced white spot lesions and after surface treatments using the DIAGNOdent®.  The fluorescence intensity differences during measurements were calculated. ANOVA and Tamhane's multiple comparison were used to analyzed the significant difference between group at 95% level of confidence. SEM and polarized light microscopy were used to determine microscopic surface alteration and depth of lesion.   

Results: The mean ± SD of fluorescence intensity differences between before and after surface treatments were:- Gr.1) 4.02 ± 0.69, Gr.2) 8.28 ± 1.60, Gr.3) 9.12 ± 1.06 and Gr.4) 9.07 ± 1.85.  There were significantly improvement of remineralization as a result of remineralized  materials used (P<0.05). Apacider® vanish was capable of remineralization potential comparable with Duraphat® and Tooth mousse® SEM and polarized light microscopy revealed an improvement of remineralized surface and decreased depth of lesion.

Conclusion: Apacider® varnish was capable of remineralization potential for the white spot lesion comparable to other remineralized materials.

 


IADR/AADR/CADR General Session
2011 IADR/AADR/CADR General Session (San Diego, California)
San Diego, California
2011
112
Cariology Research - Demin/Remineralization
  • Juntavee, Apa  ( Faculty of dentistry, Khon Kaen University, Khon-Kaen, N/A, Thailand )
  • Suksuphew, Sarunya  ( Faculty of dentistry, Khon Kaen University, Khon Kaen, N/A, Thailand )
  • Juntavee, Niwut  ( Faculty of dentistry, Khon Kaen University, Khon-Kaen, N/A, Thailand )
  • Peerapattana, Jomjai  ( Faculty of Pharmacy, Khon Kaen University, Khon-Kaen, N/A, Thailand )
  • Chatrchaiwiwattana, Supaporn  ( Faculty of dentistry, Khon Kaen University, Khon-Kaen, N/A, Thailand )
  • Luengpailin, Somkiat  ( Faculty of dentistry, Khon Kaen University, Khon-Kaen, N/A, Thailand )
    • Oral Session
    Keynote Address and Cariology: Demineralization and Remineralization
    03/16/2011