Objectives: Adhesion-promoting polymerizable cyclodextrin derivatives require compatible diluent comonomers, for example, vinybenzyl ethers of sugar alcohols. The relatively high melting points and low solubilities in easily removed volatile aprotic solvents have made candidate reactants sorbitol, xylitol, and meso-erythritol somewhat problematic during their ether-forming SN2 reactions with vinylbenzyl halides. The hypothesis was that combinations of these sugar alcohols would form lower-melting eutectics to minimize solvent requirements and permit lower reaction temperatures for less risk of premature thermal polymerization during comonomer syntheses. Methods: With a hot-stage polarizing microscope, the melting point of each of these sugar alcohols was measured. Then, each pair was thoroughly mixed and the temperature at which there was the first indication of liquid formation in the binary mixture was recorded, which was the eutectic temperature (Te) for that combination. In the equation: X1=100(T2–Te)/T1+T2–2Te the predicted mole percentage of the lower-melting component is X1, and T2 is the melting point of the higher-melting component. A ternary (triangular) plot with the three binary eutectics comprising the sides allowed for an estimation of the ternary eutectic proportions. Results: The average (n=3±sd) eutectic temperatures (Te) found were: sorbitol+xylitol: 66±0.6 °C; xylitol+meso-erythritol: 75±1.0 °C; and meso-erythritol+sorbitol: 80±0.6 °C. The ternary eutectic melted at about 57±3.6 °C. Conclusions: The hypothesis that combinations of sugar alcohols could form lower-melting eutectics was supported. The incorporation of glycerol as a sugar-alcohol reagent, if necessary to provide further lowering, will be evaluated. This work was supported by NIDCR DE05129, NIST, and the ADA/ADAF.