IADR Abstract Archives

Chlorhexidine and Fluoride Effects on Gamma Irradiated Enamel and Dentin

Objective: The effect of mouthwash protocols to prevent the gamma irradiation therapy damage on the ultimate tensile strength (UTS) of enamel and dentin is unknown. The aim of this study was analyze the effect of the use of chlorhexidine and fluoride rinsing to maintain the UTS of the human dental enamel and dentin.

Methods: Were collected 60 human teeth divided into 2 groups, irradiated (Ir), 60 Gy of gamma radiation fractioned in daily values of 2 Gy, five days a week; and non-irradiated (NIr). The teeth were subdivided into a control group (C) and 2 mouthwash protocols used 3 times a day: 0.12% chlorhexidine (Cl) and 0.05% sodium fluoride (F). The specimens were serial cut and the dental structures: enamel (E), coronal dentin (Dc) and root dentin (Dr) were tested parallel (p) and transversal (t), to prism orientation and dentin tubules by microtensile testing. Failure modes were analyzed by scanning electron microscopy.

Results: UTS means and (standard deviation) were: EpNIrC-42.6±12.9, EpNIrF-42.2±15.5, EpNIrCl-43.2±13.7; EpIrC-28.1±8.2, EpIrF-27.3±6.3, EpIrCl- 38.5±4.9; EtNIrC-18.7±4.7, EtNIrF-17.7±4.4, EpNirCl-18.0±2.0; EtIrC-10.7±3.1, EtIrF-11.0±2.6, EpIrCl-15.9±2.7; DcpNIrC-56.9±15.1 DcpNIrF-57.6±12.5, DcpNIrCl-55.1±12.1; DcpIrC-39.2±8.4, DcpIrF-45.1±7.8, DcpIrCl-39.6±7.6; DctNIrC-90.4±15.6, DctNIrF-89.4±16.7, DctNIrCl-91.6±16.9; DctIrC-54.6±10.7, DctIrF-76.2±12.5, DctIrCl-53.2±13.1; DrtNIrC-50.7±10.1, DrpNIrF-51.7±13.4, DrpNIrCl-52.1±13.2; DrpIrC-34.6±12.5, DrpIrF-32.5±7.3, DrpIrCl-34.2±8.5; DrtNIrC-69.2±11.4, 67.4±15.2, 68.2±16.5; DrtNIrF-52.1±19.0, 50.0±12.5, DrtNIrCl-53.2±10.3. The Tukey test (P <0.05) revealed that the presence of irradiation reduces the UTS of enamel, crown and root dentin regardless of the orientation of the prisms and tubules.

Conclusion: The rinsing with chlorhexidine 0.12% prevent partially the damage of the mechanical properties of crown dentin irradiated and that 0.05% sodium fluoride recovered the UTS of enamel irradiated similarly to the non-irradiated enamel.


Division: IADR/PER General Session
Meeting: 2010 IADR/PER General Session (Barcelona, Spain)
Location: Barcelona, Spain
Year: 2010
Final Presentation ID: 4553
Abstract Category|Abstract Category(s): Dental Materials 5: Biocompatibility and Biologic Effects
Authors
  • Soares, Priscilla  ( Federal University of Uberlândia, Uberlândia, N/A, Brazil )
  • Neiva, Natália  ( Federal University of Uberlândia, Uberlândia, N/A, Brazil )
  • Fernandes Neto, Alfredo  ( Federal University of Uberlândia, Uberlândia, N/A, Brazil )
  • Magalhães, Denildo  ( Federal University of Uberlândia, Uberlândia, N/A, Brazil )
  • Soares, Carlos J.  ( Federal University of Uberlândia, Uberlândia, N/A, Brazil )
  • SESSION INFORMATION
    Poster Session
    Biocompatibility and Biologic Effects IV
    07/17/2010