The Effectiveness of Hexetidine 0,1% Mouthwash to Prevent Transient Bacteremia

Transient bacteremia always occurs following tooth extraction, this could leads to focal infection to other parts of the body. Objectives: The aim of the study is to evaluate the effectiveness of hexetidine 0.1% as mouthwash prior to tooth extraction to prevent bacteremia after tooth extraction. Methods: 60 consecutive patients come to ask for tooth extraction in Oral and Maxillofacial Department of Dental Hospital Faculty of Dentistry Universitas Indonesia, were asking to become subjects of this study. Sample was divided into 2 groups. First group, patients were gargled with Hexetidine 0,1%; second group as control, patients were gargled with Sodium chloride 0,9 % before tooth extraction. 5 and 10 minutes after tooth extraction blood was collected from v.cubitus of each patient for bacterial evaluation. Data obtained was analyzed with Chi-square test. Results: 5 minutes after tooth extraction, in group 1: 4 (13%) and group 2: 22 (73%) blood sample were positive contaminated with aerob bacterial. And blood sample which positive contaminated with anaerob bacterial in group 1: 10 (33%) and group 2: 24 (80%). Statistic analyzis confirmed that there are significance difference gargled with hexetidine 0,1% than Sodium Chloride 0.9%. (p > 0,05). 10 minutes after tooth extraction minimal bacterial found in blood sample and there are no significance different between those 2 groups. Conclusion: Using hexetidine 0,1% as mouth gargle before tooth extraction is effective to prevent transient bacteremia after tooth extraction either aerob or anaerob bacterial.

Keywords : Hexetidine 0,1%, Transient Bacteremia