18F-FDG uptake level was diminished in chronically painful trapezius muscle
Objectives: We evaluated the relationship between the chronic trapezius muscle pain and the uptake value of 18F-fluorodeoxyglucose (FDG) in the muscle tissue to clarify the metabolic state in painful muscle tissues. Methods: Consecutive 167 non-cancer subjects who had a PET/CT screening for physical check up at Okayama Diagnostic Imaging Center from May to August 2007 participated in this study (mean age: 56.0+/-10.2 years, male/female=114/53). The demographic data and pain existence/absence and intensity in neck/shoulder region were obtained using a questionnaire before PET/CT scan. PET/CT scan was performed 90 min after i.v. infusion of 18F-FDG (3.7 MBq/Kg) and the data were gathered using a PET/CT scanner (biograph LSO/Sensation 16, SIEMENS, slice thickness: 2 mm). The region of interest (ROI) was set in the cross-sectional slice of trapezius muscle using anatomic landmarks evident on the PET/CT image (The slice level, which depicts the superior end of acromion). This ROI was set to contain the upper portion of the trapezius muscle. The standardized uptake value (SUV) of 18F-FDG of ROI was automatically calculated by using the open source image processing software (OsiriX2, Osirix Foundation, Geneva, Switzerland). The data of the questionnaire items (gender, age, smoking history, medical history, awareness and level of chronic trapezius muscle pain) and the minimal and maximal SUVs of each subject were submitted for multiple regression analysis. Results: As the result of the statistical analysis, significant correlation was observed between the presence of chronic trapezius muscle pain and SUVs. The significant associations were seen whichever SUVs (minimal or maximal) was evaluated (p<0.0001, respectively). Furthermore, the Pearson correlation revealed that the higher the pain level in neck/shoulder region was, the lower the SUVs were (p<0.01, respectively). Conclusion: These results indicated the possibility that metabolic activity is diminished in chronically painful trapezius muscle.
Division: IADR/AADR/CADR General Session
Meeting:2009 IADR/AADR/CADR General Session (Miami, Florida) Location: Miami, Florida
Year: 2009 Final Presentation ID:1432 Abstract Category|Abstract Category(s):Neuroscience / TMJ
Authors
Takiguchi, Satoru
( Okayama University, Okayama, N/A, Japan
)
Maekawa, Kenji
( Okayama University, Okayama, N/A, Japan
)
Ono, Tsuyoshi
( Okayama University, Okayama, N/A, Japan
)
Sasai, Nobuya
( Okayama Diagnostic Imaging Center, Okayama, N/A, Japan
)
Kaji, Mitsumasa
( Okayama Diagnostic Imaging Center, Okayama, N/A, Japan
)
Matsuka, Yoshizou
( Okayama University, Okayama, N/A, Japan
)
Clark, Glenn T.
( University of Southern California, Los Angeles, CA, USA
)
Kuboki, Takuo
( Okayama University, Okayama, N/A, Japan
)