Clinical Effect of an Chlorhexidine and Aluminiumlactate Containing Dentifrice

Objectives: The aim of the study was to determine the plaque and gingivitis reducing effect of a dentifrice containing chlorhexidine and aluminium lactate compared to a placebo toothpaste during a course of 6 months. Methods: In this 6 month randomized, double-blind, prospective, parallel group study, plaque, gingivitis, calculus formation and tooth staining were assessed in 59 participants. The participants either used a chlorhexidine and aluminium lactate containing toothpaste (test group) or a placebo toothpaste (control group). Parameters were assessed at baseline and after 1, 3 and 6 months. Results: After 6 months of product use, both groups had less gingivitis compared to the baseline evaluation (p<0.001). Statistically significant reduction in gingivitis was also seen for the test group compared to the control group (p=0.001). Plaque Index and development of calculus and staining showed neither statistically significant differences between the groups nor between the time points. Conclusion: It is concluded that the tested dentifrice may contribute to a significant improvement in gingival conditions without developing unfavourable side effects like tooth staining. This study was financially supported by Arcam, Germany