Experimental Methods: Criteria for inclusion: examination of panoramic radiographs of early mixed dentition (~8-10 years old), bilateral distal inclination of unerupted second premolar tooth buds and evaluation of cephalometric radiographs using Witt's Analysis. Distal inclination is defined as at least 10 degree decrease of the angle between long axis of developing tooth and inferior border of mandible.
Results: Over 2500 cases were screened, of which 21 cases matched the inclusion criteria. An average degree of second premolar distal inclination was 66.5 (range 50-77) 10 out of 21 exhibited cephalometric Class III skeletal growth patterns. Initial findings suggest that distal inclination is a reliable predictor of developing Class III malocclusion. 10 out of 21 subjects have been confirmed to exhibit characteristics of developing Class III malocclusion.
Conclusion: In addition to its use as a diagnostic tool for dental development, in certain instances panoramic radiographs can be used as a diagnostic predictor of skeletal growth. Further studies should determine whether the degree of pre-eruptive compensation correlates with the severity of Class III malocclusion.