Objective: The purpose of this study was to investigate the remineralization effect of bamboo salt in dentifrice containing fluoride with a silica abrasive formula using the chemical pH cycling model. Methods: Specimens of bovine tooth enamel were embedded in resin, polished, exposed to a lactate carbopol buffer system for 44 hours, and divided 4 groups (negative control, positive control containing NaF (0.22%) 1,000 ppm, Crest Cavity Protection (Procter & Gamble) containing NaF and test dentifrices containing NaF (0.22%) 1,000 ppm and bamboo salt 3.0% with a silica abrasive formula) of 12 specimens each by randomized blocks with Vicker's hardness number(VHN) stratification. Surface hardness was compared before and after the chemical pH cycling sequences for 20 days. Results: The differences of before and after VHN (DVHN) were 26.35±6.76 in negative control, 121.71±34.14 in positive, 135.31±26.75 in Crest Cavity Protection and 158.79±13.81 in test dentifrice. Statistical analyses of these results indicated that positive control, Crest Cavity Protection and test dentifrices containing NaF were significantly more effective than that of negative control (p<0.05). Test dentifrice with bamboo salt was significantly more effective than those of without bamboo salt (p<0.05), but there was no difference between positive control and Crest Cavity Protection (p>0.05) on surface hardening in chemical pH cycling model. Conclusion: The dentifrice containing NaF and bamboo salt showed a greater effect on the remineralization of the incipient caries lesion than the other groups in chemical pH cycling model.