Objectives: New developments in adhesive dentistry include self-etching adhesives and nanofilled composites. The null hypothesis tested in this in vitro study was that the combination of a self-etching adhesive, Adper Prompt (ADP, 3M ESPE), with a nanofilled composite (Filtek Supreme, SUP, 3M ESPE) would not result in greater microleakage than that obtained with phosphoric acid etching followed either by a nanofilled composite or an universal hybrid composite . Methods: Class Vs were prepared in the lingual and buccal aspects of thirty caries-free extracted third molars, with one margin in dentin/cementum and the other in enamel. Specimens were randomly assigned to three groups: (1) ADP+ SUP; (2) Single Bond (3M ESPE) + SUP; (3) Excite + Tetric
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Restorative | Enamel | Dentin | ||
| >M | £M | >M | £M | |
| Adper Prompt + Supreme | 7 | 3 | 6 | 4 |
| Single Bond + Supreme | 3 | 7 | 3 | 7 |
| Excite + Tetric | 3 | 7 | 6 | 4 |
The null hypothesis was accepted. Adper Prompt combined with Filtek Supreme resulted in statistically similar dentin (p>0.301) and enamel (p>0.114) microleakage scores than Single Bond + Filtek Supreme or Excite+Tetric