Pulp Capping with an Experimental Hemostatic Agent and Calcium Hydroxide

Complete control over hemostasis is considered to be a critical factor in obtaining predictable favorable results in pulp capping procedures. Saline, 2% chlorhexidine and various concentrations of sodium hypochloride have been reported in the literature as being suitable. Objective:It was the objective of this experiment to determine the efficacy of an experimental hemostatic solution in pulp capping procedures. Methods:84 Cl V preparations were made in six primates divided over 4 groups. After exposure of the pulp, this non-epinephrine experimental solution was applied using a sterile cotton pellet and left in place for + 5 minutes. Two groups had Consepsis, a disinfecting solution, applied for 60s. A small amount of calcium hydroxide (Ultrablend Plus) was placed over the exposures. After light curing the cavities were restored using an acid etch/bonding agent/resin composite technique. Animals were euthanized with an overdose of ketamine and the jaws fixed in 10% neutral buffered formalin. All teeth were processed for routine histological evaluation. Three time periods were evaluated. Results: After 5 days the pulps were remarkable for minor inflammation (0.5-1.33 degrees). After 25 days only one group scored 0.18 degrees, after 75 days no inflammation was seen. All specimens after 25 and 75 days (a total of 27) were vital and had a bridge, with a quality ranging from 1.71-2.6 degrees (on a scale of 1-3). Conclusions: the experimental solution was a successful hemostatic agent, establishing a controlled environment, which allowed for the application of a light cured calcium hydroxide, resulting in predictable bridge formation. Disinfecting with 2% chlorhexidine is recommended. (Supported by Ultradent Products Inc). phpameijer@home.com