Aphthous Stomatitis and Oral Candidiasis in Patient with HIV Infection

Objectives: HIV infection can cause severe damage to immune system due to destroyed CD4+ cells. This condition makes HIV-infected person vulnerable to opportunistic infection, including oral candidiasis. Oral candidiasis can be the early clinical features of someone having immunity impairment. The immunodeficiency state in HIV infected patients has been the cause of severe episodes of Recurrent Aphthous Stomatitis (RAS), leading to nutritional deficit and poor quality of life. This article presents a case of major recurrent aphthous stomatitis and oral candidiasis as manifestation of immunodeficiency state in HIV infection. A 48 -year- old female complained of painful lesions dispersed in her tongue and corner of the lips causing disturbance while eating due to severe pain. Patient had been diagnosed with HIV-AIDS since early 2018. Patient’s general condition was poor. Extraoral examination showed ulcer surrounded by reddened crust. Intraoral examination showed extensive painful ulcer on dorsal tongue and white pseudomembrane which could be scraped off leaving reddened layer on tongue.
Methods: Management included anamnesis, clinical examination, and laboratory examination of complete blood panel and swab from the pseudomembrane layer then performing direct and indirect mycology examination. Patient was instructed to take medicine regularly. Patient was given nystatin 100.000 IU, fluconazole 150 mg and Anti Retro Viral by internist and was prescribed oxyfresh dental gel. The lesion healed in 14 days.
Results: Clinical Case, not applicable.
Conclusions: Clinical Case, not applicable.