IADR Abstract Archives
Tooth Color Improvement with use of a Low-concentration H2O2 Strip
Objectives: This randomized, parallel design clinical study assessed changes in tooth color with use of a low-concentration H2O2 whitening strip compared to a negative control.
Methods: Institutional review and informed consent were obtained, and subjects with no previous history of teeth whitening were randomly assigned to either high-adhesion 5.25% H2O2 tooth whitening strips (Crest ® 3D White Whitestrips® Gentle Routine) or Crest® Cavity Protection toothpaste. Subjects were instructed to brush twice daily in the customary manner. Subjects in the strip group used one strip per day for 30 minutes for 14 days. Whitening efficacy was assessed as L*a*b* color change from digital images of the maxillary anterior teeth at Baseline, Day 11 and Day 15.
Results: A total of 60 subjects were enrolled and completed the study. Study participants ranged in age from 18 to 65 with mean age of 39.8 years. At Day 11 and at Day 15, the strip group exhibited a statistically significant (p<0.0001) reduction in yellowness (Δb*) and improvement in lightness (ΔL*) compared to baseline. The paste group did not have a statistically significant (p>0.29) change in yellowness at either time point. At both Day 11 and Day 15 visits, the use of low-concentration H2O2 strips demonstrated significantly (<0.007) greater b* and L* color improvement relative to the paste group. The adjusted mean Δb* values for strip and paste groups were -1.24 and -0.10, and -1.43 and -0.10 at Day 11 and Day 15, respectively. The adjusted mean ΔL* values for strip and paste groups were 1.10 and 0.51, and 1.31 and 0.33 at Day 11 and Day 15, respectively.
Conclusions: Use of 5.25% H2O2 high-adhesion whitening strips results in significant tooth color improvement.
Methods: Institutional review and informed consent were obtained, and subjects with no previous history of teeth whitening were randomly assigned to either high-adhesion 5.25% H2O2 tooth whitening strips (Crest ® 3D White Whitestrips® Gentle Routine) or Crest® Cavity Protection toothpaste. Subjects were instructed to brush twice daily in the customary manner. Subjects in the strip group used one strip per day for 30 minutes for 14 days. Whitening efficacy was assessed as L*a*b* color change from digital images of the maxillary anterior teeth at Baseline, Day 11 and Day 15.
Results: A total of 60 subjects were enrolled and completed the study. Study participants ranged in age from 18 to 65 with mean age of 39.8 years. At Day 11 and at Day 15, the strip group exhibited a statistically significant (p<0.0001) reduction in yellowness (Δb*) and improvement in lightness (ΔL*) compared to baseline. The paste group did not have a statistically significant (p>0.29) change in yellowness at either time point. At both Day 11 and Day 15 visits, the use of low-concentration H2O2 strips demonstrated significantly (<0.007) greater b* and L* color improvement relative to the paste group. The adjusted mean Δb* values for strip and paste groups were -1.24 and -0.10, and -1.43 and -0.10 at Day 11 and Day 15, respectively. The adjusted mean ΔL* values for strip and paste groups were 1.10 and 0.51, and 1.31 and 0.33 at Day 11 and Day 15, respectively.
Conclusions: Use of 5.25% H2O2 high-adhesion whitening strips results in significant tooth color improvement.