IADR Abstract Archives
Clinical Effectiveness of Toothpaste Containing REFIX Technology Against Dentin Hypersensitivity
Objectives: This clinical study aimed to evaluate the efficacy of a novel multifunctional phosphate-based toothpaste containing REFIX Technology against dentin hypersensitivity.
Methods: Fifty-three volunteers who fulfilled the inclusion criteria and signed the consent form were selected. Patients were examined for dentin hypersensitivity sensitivity. The patients were given a blast of air for 10 seconds and the tooth sensitivity was immediately evaluated by visual analogue scale (VAS), from 0 to 10. Then, dentin hypersensitivity was tested for the second time after patients brushing their teeth with the multifunctional toothpaste, reporting the VAS again. Finally, the patients were asked to report the VAS after one week of continuous use of the toothpaste (at least two times a day). A non-parametric test was used (α=5%) to analyze the results following a normality test of the VAS.
Results: The mean age of the patients was 40 years old, and 70 % of the 53 subjects were female. The statistical analysis demonstrated a significant reduction in the dentin hypersensitivity. The mean immediate pain reported by the patients was severe pain (6.5). Immediately after the first use of the toothpaste, the mean reported pain significantly dropped to mild pain (2.5) (p <0.05). Moreover, 1 out of 3 patients decreased the reported pain from severe to painless after immediate use of the toothpaste. After one week of continuous use of the toothpaste patients reported no pain (0.7), demonstrating the effectiveness of the REFIX Technology against dentin hypersensitivity (p<0.05).
Conclusions: This clinical trial showed that the use of the novel multifunctional phosphate-based desensitizing toothpaste containing REFIX Technology significantly reduces the dentin hypersensitivity after one week of continuous use.
Methods: Fifty-three volunteers who fulfilled the inclusion criteria and signed the consent form were selected. Patients were examined for dentin hypersensitivity sensitivity. The patients were given a blast of air for 10 seconds and the tooth sensitivity was immediately evaluated by visual analogue scale (VAS), from 0 to 10. Then, dentin hypersensitivity was tested for the second time after patients brushing their teeth with the multifunctional toothpaste, reporting the VAS again. Finally, the patients were asked to report the VAS after one week of continuous use of the toothpaste (at least two times a day). A non-parametric test was used (α=5%) to analyze the results following a normality test of the VAS.
Results: The mean age of the patients was 40 years old, and 70 % of the 53 subjects were female. The statistical analysis demonstrated a significant reduction in the dentin hypersensitivity. The mean immediate pain reported by the patients was severe pain (6.5). Immediately after the first use of the toothpaste, the mean reported pain significantly dropped to mild pain (2.5) (p <0.05). Moreover, 1 out of 3 patients decreased the reported pain from severe to painless after immediate use of the toothpaste. After one week of continuous use of the toothpaste patients reported no pain (0.7), demonstrating the effectiveness of the REFIX Technology against dentin hypersensitivity (p<0.05).
Conclusions: This clinical trial showed that the use of the novel multifunctional phosphate-based desensitizing toothpaste containing REFIX Technology significantly reduces the dentin hypersensitivity after one week of continuous use.