Comparison Between Chlorhexidine And Silver Fluoride Diamine For Cavity Cleaning

Objectives: This randomized clinical trial study aims to compare different cavity cleaning agents.
Methods: Two Diamino fluoride solutions at concentrations of 38%, 30% and a 2% chlorhexidine solution were studied. Were selected 40 children between 7 and 10 years of age with Black caries classification class I, in deciduous molars.
The sample was randomly divided into four groups: (G1) 38% silver fluoride diamine; (G2) 30% silver fluoride diamine; (G3) 2% chlorhexidine solution and (G4) control group. During the clinical examination, the carious lesions were identified, classified and radiographed. The teeth were treated in the subsequent session according to the division of the groups. The dentin samples were collected before and after application of each cleaning agent in the same session, following the manufacturer's instructions and taken for laboratory analysis, where they were divided into two groups: diluted and undiluted.
The diluted group was cultured, in brain heart infusion (BHI) culture medium that was used to grow and count the total microorganisms after being incubated anaerobically at 37 °C for 72 hours.
The undiluted samples were cultured in Mitis Salivarius medium, that allows selective growth of Streptococcus mutans. These samples were incubated under microaerophilic conditions at 37 ° C for 48 hours.
Results: The results suggest that the G2 presented a lower number of total microorganisms after the application of 30% silver diamine fluoride, followed by G1 and G3 and the worst G4. In relation to Streptococcus mutans, G2 also showed superiority in the results, being able to inhibit the growth in 99, 92% of the plates, G1 reduced this growth in 45.45% of the plaques and G3 and G4 were not effective in inhibiting the growth.
Conclusions: Silver fluoride diamine was more effective than chlorhexidine when used to reduce total microorganisms. The two diamino fluoride formulations have similar mechanisms of action, although the 30% silver fluoride diamine shows superiority in the results.