IADR Abstract Archives
Clinical Evaluation of a Baking Soda Dentifrice on Gum Health
Objectives: Evaluate and compare the effectiveness of a baking soda dentifrice, Arm&Hammer™ AdvanceWhite™ Breath Freshening [20% baking soda(BS)] versus negative control, Crest® Cavity Protection Regular (0% BS) in reducing plaque and gingivitis following 3-months of product use.
Methods: This was a single-center, double-blind, parallel-group, randomized, study. One-hundred fifty-nine qualifying subjects with Soparkar/Turesky modified plaque index scores (PI)≥2.0, modified gingival index scores (MGI)≥1.80 and ≥10 gingival bleeding (GBI) sites, were randomized to one of two treatment groups. Clinical assessments for oral soft/hard tissue, plaque, gingival inflammation and bleeding were conducted after 4 and 8-weeks, and 3-months of product use. At the conclusion of the 3-month treatment phase, all subjects were instructed to return to their same oral hygiene regimen, that they used prior to the study, and brushed for an additional 4-weeks to evaluate long lasting effects.
Results: One-hundred fifty-six subjects (78/group), completed the study. Mean MGI, GBI and PI scores for both dentifrices showed statistically significant within-treatment reductions versus baseline. For every parameter, (MGI-GBI-PI) and at each time point, of the 3-month study, the 20% BS dentifrice was statistically significantly more effective (p<0.01) than the control, 0% BS. At month 3, the 20% BS dentifrice showed a significantly greater reduction in MGI(12.6%), GBI(44.2%) and PI(9.6%), versus the control. Four-week long-lasting effects showed that, although plaque levels for subjects who brushed with the 20% BS dentifrice during the 3-month study showed similar levels of plaque versus control, they nonetheless had statistically significantly (p≤0.0001) lower MGI(9.2%) and GBI(44.6%) scores compared to control group.
Conclusions: This 3-month clinical study showed that a 20% BS dentifrice was significantly more effective in the reduction of gingival inflammation, bleeding and plaque compared to a regular dentifrice. Additionally, the 20% BS dentifrice showed a long-lasting effect for gingival inflammation and bleeding reduction versus the negative control.
Methods: This was a single-center, double-blind, parallel-group, randomized, study. One-hundred fifty-nine qualifying subjects with Soparkar/Turesky modified plaque index scores (PI)≥2.0, modified gingival index scores (MGI)≥1.80 and ≥10 gingival bleeding (GBI) sites, were randomized to one of two treatment groups. Clinical assessments for oral soft/hard tissue, plaque, gingival inflammation and bleeding were conducted after 4 and 8-weeks, and 3-months of product use. At the conclusion of the 3-month treatment phase, all subjects were instructed to return to their same oral hygiene regimen, that they used prior to the study, and brushed for an additional 4-weeks to evaluate long lasting effects.
Results: One-hundred fifty-six subjects (78/group), completed the study. Mean MGI, GBI and PI scores for both dentifrices showed statistically significant within-treatment reductions versus baseline. For every parameter, (MGI-GBI-PI) and at each time point, of the 3-month study, the 20% BS dentifrice was statistically significantly more effective (p<0.01) than the control, 0% BS. At month 3, the 20% BS dentifrice showed a significantly greater reduction in MGI(12.6%), GBI(44.2%) and PI(9.6%), versus the control. Four-week long-lasting effects showed that, although plaque levels for subjects who brushed with the 20% BS dentifrice during the 3-month study showed similar levels of plaque versus control, they nonetheless had statistically significantly (p≤0.0001) lower MGI(9.2%) and GBI(44.6%) scores compared to control group.
Conclusions: This 3-month clinical study showed that a 20% BS dentifrice was significantly more effective in the reduction of gingival inflammation, bleeding and plaque compared to a regular dentifrice. Additionally, the 20% BS dentifrice showed a long-lasting effect for gingival inflammation and bleeding reduction versus the negative control.