IADR Abstract Archives
Lactic Acid Bacteria Metabolite-containing Gummies Improve Oral Health
Objectives: Recently, the consumption of probiotics to prevent oral diseases has been attracting attention. In our laboratory, administration of Lactobacillus rhamnosus KO3 (L8020), isolated from the resting saliva of an individual without a history of dental caries, markedly decreased the growth of cariogenic fungi, pathogenic fungi, and periodontal disease-causing bacteria. In addition, consuming L8020-containing yoghurt decreases the number of cariogenic fungi in the oral cavity. And the number of periodontal disease causing bacteria highly inhibit on oral pathogenic bacteria by ingesting tablets containing L8020. Based on these studies, we attempted to produce L8020 lactic acid bacteria metabolite-containing gummies. In this study, we investigated the effect of L8020 lactic acid bacteria metabolite-containing gummies on oral health.
Methods: Fifty-four healthy adults (35 males, 19 females) were divided into 2 groups. One group took a placebo (P group) for 3 months and the other took the L8020 gummies (L group) for 3 months. Oral examination was performed at the start of the treatment, and then after 1, 2, and 3 months of treatment. A plaque control record (PCR) was maintained, and tests were performed for halitosis; the number of caries-causing bacteria, acidity, buffer capacity, white blood cell count, protein quantification, and ammonia amount in the saliva; and gingival health (intraoral photograph). Statistical analysis was conducted using an independent sample test.
Results: Comparing the starting time with the respective months in PCR, in both P and L groups, there was a significant decrease in every month. Between the groups, the L group had significantly decreased the dental plaques throughout. Forty-four percent of the P group and 62% of the L group showed improvement in gingival condition during the study.
Conclusions: Overall, it was observed that plaque formation was suppressed and gingival condition improved after consumption of L8020 lactic acid bacteria metabolite-containing gummies for 3 months.
Methods: Fifty-four healthy adults (35 males, 19 females) were divided into 2 groups. One group took a placebo (P group) for 3 months and the other took the L8020 gummies (L group) for 3 months. Oral examination was performed at the start of the treatment, and then after 1, 2, and 3 months of treatment. A plaque control record (PCR) was maintained, and tests were performed for halitosis; the number of caries-causing bacteria, acidity, buffer capacity, white blood cell count, protein quantification, and ammonia amount in the saliva; and gingival health (intraoral photograph). Statistical analysis was conducted using an independent sample test.
Results: Comparing the starting time with the respective months in PCR, in both P and L groups, there was a significant decrease in every month. Between the groups, the L group had significantly decreased the dental plaques throughout. Forty-four percent of the P group and 62% of the L group showed improvement in gingival condition during the study.
Conclusions: Overall, it was observed that plaque formation was suppressed and gingival condition improved after consumption of L8020 lactic acid bacteria metabolite-containing gummies for 3 months.