IADR Abstract Archives
Association Between Periodontal Disease and Carotid Intima-Media Thickness
Objectives: The purpose of this study was to establish the association between periodontal disease and carotid intima-media thickness (c-IMT)
Methods: A cross-sectional study was conducted with 70 participants over 30 years of age, who had not received periodontal treatment, or antibiotic treatment in the last three months. Exclusion criteria: patients with diabetes and smokers. A clinical history was realized, periodontal examination and diagnosis, and maximal cIMT measurement were performed for each. All patients had a blood count, triglycerid count, total cholesterol, HDL, LDL and basal glycemia. The measurement of the c- IMT was determined with the use of ultrasonography. The IMT of the distal wall of the carotid and the presence of plaque was evaluated according to the Mannheim consensus. The measurements were made on a length of 10mm and were then averaged.
We made a description of the demographic characteristics and the results of the periodontal evaluation, the thickness of carotid intima-media (c-IMT), through means, medians, ranges, standard deviations and Confidence Intervals of 95%.
Results: 70 patients were analyzed, 35 with gingivitis and 35 with severe chronic periodontitis. Patients with gingivitis had an average age of 42,5 years, while patients with periodontitis were, on average, 54,7 years old. The thickness of carotid intima-media was greater in patients with periodontitis (c-IMT 0,66 Right 0.72 Left) that in patients with gingivitis ((c-IMT 0.60 Right, 0.58 left), without any significant statistical differences. ( Graph 1). A trend was identified within patients with abnormal IMT (Abnormal C-IMT ≥0.9) in which a greater number displayed severe chronic periodontitis, although there were no significant statistical differences
Conclusions: The results of this research showed that patients with periodontal disease had a greater thickness in the carotid intima-media (c-IMT). Likewise, patients with abnormal IMT displayed more severe periodontitis, although there were no significant statistical differences. Future prospective studies are needed to confirm this association.
Methods: A cross-sectional study was conducted with 70 participants over 30 years of age, who had not received periodontal treatment, or antibiotic treatment in the last three months. Exclusion criteria: patients with diabetes and smokers. A clinical history was realized, periodontal examination and diagnosis, and maximal cIMT measurement were performed for each. All patients had a blood count, triglycerid count, total cholesterol, HDL, LDL and basal glycemia. The measurement of the c- IMT was determined with the use of ultrasonography. The IMT of the distal wall of the carotid and the presence of plaque was evaluated according to the Mannheim consensus. The measurements were made on a length of 10mm and were then averaged.
We made a description of the demographic characteristics and the results of the periodontal evaluation, the thickness of carotid intima-media (c-IMT), through means, medians, ranges, standard deviations and Confidence Intervals of 95%.
Results: 70 patients were analyzed, 35 with gingivitis and 35 with severe chronic periodontitis. Patients with gingivitis had an average age of 42,5 years, while patients with periodontitis were, on average, 54,7 years old. The thickness of carotid intima-media was greater in patients with periodontitis (c-IMT 0,66 Right 0.72 Left) that in patients with gingivitis ((c-IMT 0.60 Right, 0.58 left), without any significant statistical differences. ( Graph 1). A trend was identified within patients with abnormal IMT (Abnormal C-IMT ≥0.9) in which a greater number displayed severe chronic periodontitis, although there were no significant statistical differences
Conclusions: The results of this research showed that patients with periodontal disease had a greater thickness in the carotid intima-media (c-IMT). Likewise, patients with abnormal IMT displayed more severe periodontitis, although there were no significant statistical differences. Future prospective studies are needed to confirm this association.
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