Fluoride Concentration in Silver Diamine Fluoride Commercial Products
Objectives: Different commercial silver diamine fluoride (SDF) products are available to arrest and prevent coronal caries in primary teeth but there are no data evaluating fluoride concentration in these formulations. Also, these products should be formulated to follow the chemical formula AgF(NH3)2 but it is not known if they are properly manufactured with this stoichiometry. Therefore, the aim of this study was to determine fluoride concentration in six SDF products. Methods: The products evaluated were (n=1): I: Cariostasul 10% (Expected 11,809 ppm F, Iodontosul, Brazil), II: Ancárie 12% (Expected 14,170 ppm F, Maquira, Brasil); III: Ancárie 30% (expected 35,426 ppm F, Maquira, Brazil), IV: Cariestop 12% (expected 14,170 ppm F, Biodinamica, Brazil); V: Cariestop 30% (expected 35,426 ppm F, Biodinamica, Brazil) and VI: Advantage Arrest 38.3 to 43.2%, w/v, (expected 45,283 to 51,013 ppm F, Elevate Oral Care, USA). Advantage Arrest was purchased in USA market and the others in Brazil. The products were diluted by volume in purified water, buffered with TISAB II and fluoride concentration in the solutions was determined with ion specific electrode calibrated with standards ranging from 4 to 64 µg F/mL. The dilutions were made in duplicate from one flask of each product and the readings were also made in duplicates. The results were expressed in ppm (µg F/mL). Results: The fluoride ion concentrations (mean±SD) found were I. 23,328.1±1,160.9; II. 4,753.6±148.2; III. 5,668.3±271.4; IV. 8,908.7±548.7; V. 11,170.3±135.3 and VI. 53,728.1±3,164.4 ppm F. Conclusions: Only one SDF product was properly formulated to follow the formula AgF(NH3)2 . This study was conducted during the discipline In Vitro Models in Cariology, from Piracicaba Dental School, UNICAMP.
Division: IADR/AADR/CADR General Session
Meeting:2017 IADR/AADR/CADR General Session (San Francisco, California) Location: San Francisco, California
Year: 2017 Final Presentation ID:1856 Abstract Category|Abstract Category(s):Cariology Research-Fluoride & Ca-based Products
Authors
Tenuta, Livia
( Piracicaba Dental School, University of Campinas
, Piracicaba
, Brazil
)
Dala Rosa Silva, Rossano
( State University of Maringá
, Maringá
, Brazil
)
Tabchoury, Cinthia
( Piracicaba Dental School, University of Campinas
, Piracicaba
, Brazil
)
Cury, Jaime
( Piracicaba Dental School, University of Campinas
, Piracicaba
, Brazil
)
Soares, Aline
( Piracicaba Dental School, University of Campinas
, Piracicaba
, Brazil
)
Spinola, Manuela
( Piracicaba Dental School, University of Campinas
, Piracicaba
, Brazil
)
Leal, Aila
( Federal University of Piauí
, Teresina
, Brazil
)
Assis, Ana Camila
( Piracicaba Dental School, University of Campinas
, Piracicaba
, Brazil
)
Mota, Brenda
( Federal University of Piauí
, Teresina
, Brazil
)
Da Silva, Daylana
( Federal University of Piauí
, Teresina
, Brazil
)
Tsuzuki, Fernanda
( State University of Maringá
, Maringá
, Brazil
)
De Sousa, Geovanna
( Federal University of Piauí
, Teresina
, Brazil
)