IADR Abstract Archives
Root Canal Medicament: Mixture of Calcium Silicate-based Cement and Chlorhexidine Gel
Objectives: To evaluate the physical properties of Calcium Silicate-based Cement (CSC) after mixing with 2% Chlorhexidine gel (CHX) to be used as root canal medicament.
Methods: Three types of CSC were used in this study: white Portland cement (Aalborg, Malaysia), white ProRoot MTA (Tulsa, USA), and Biodentine (Septodont, France). CSCs were mixed with 2% CHX (n=8) with ratio of (2g powder:1g CHX). Calcium Hydroxide paste (Master-Dent, UAS) was used as a control in this study. The setting time, calcium ion release, pH of the water surrounding the specimens, film thickness and flowability of the CSC/CHX mixture (experimental cements) were assessed and measured following the standards of the ISO specification. Differences in materials and changes over time were compared with ANOVA and Tukey’s post-hoc tests at a significance level of 0.05.
Results: The setting time of the CSC/CHX mixture was not set until 84 days. Calcium ion release of the experimental cements was significantly higher compared to control over the period of 14 days (P<0.001). The mean pH value was above 11.45 for all materials tested in this study over the period of 14 days, however, there was a statistical significant difference between them (P<0.001). The results also showed that there was no significant difference in film thickness of the experimental cements compared to control (P>0.05), however, the results of the flowability of the experimental cements was significantly higher than the control (P<0.05).
Conclusions: The addition of 2% CHX to CSCs is retarding or inhibiting its setting reaction over a period of 84 days. The calcium ion release and flowability of this CSC/CHX mixture cement were found to be better than Calcium Hydroxide. Therefore, this experimental cement has the potential to be used as an enhanced root canal medicament. Further research on this formulation (particularly biocompatibility and antibacterial properties) is needed.
Methods: Three types of CSC were used in this study: white Portland cement (Aalborg, Malaysia), white ProRoot MTA (Tulsa, USA), and Biodentine (Septodont, France). CSCs were mixed with 2% CHX (n=8) with ratio of (2g powder:1g CHX). Calcium Hydroxide paste (Master-Dent, UAS) was used as a control in this study. The setting time, calcium ion release, pH of the water surrounding the specimens, film thickness and flowability of the CSC/CHX mixture (experimental cements) were assessed and measured following the standards of the ISO specification. Differences in materials and changes over time were compared with ANOVA and Tukey’s post-hoc tests at a significance level of 0.05.
Results: The setting time of the CSC/CHX mixture was not set until 84 days. Calcium ion release of the experimental cements was significantly higher compared to control over the period of 14 days (P<0.001). The mean pH value was above 11.45 for all materials tested in this study over the period of 14 days, however, there was a statistical significant difference between them (P<0.001). The results also showed that there was no significant difference in film thickness of the experimental cements compared to control (P>0.05), however, the results of the flowability of the experimental cements was significantly higher than the control (P<0.05).
Conclusions: The addition of 2% CHX to CSCs is retarding or inhibiting its setting reaction over a period of 84 days. The calcium ion release and flowability of this CSC/CHX mixture cement were found to be better than Calcium Hydroxide. Therefore, this experimental cement has the potential to be used as an enhanced root canal medicament. Further research on this formulation (particularly biocompatibility and antibacterial properties) is needed.