IADR Abstract Archives

Evaluation of Maternal Periodontitis as an Independent Risk Factor for Adverse Pregnancy Outcomes: A Cross-sectional Study

Objectives: The study aims to evaluate the association between maternal periodontitis and pre-term and/or low birth weight babies after the adjustment of possible confounding factors in the South Indian population.
Methods: The study involved selection of 3500 postpartum mothers from various hospitals of Tamil Nadu and they were grouped into four categories; Group I Normal term Normal birth weight (n=1100), Group-II Pre-term Normal birth weight (n=400), Group III Pre-term Low birth weight (n=1000) Group IV Normal term Low birth weight(n=1000). Socio-demographic data and personal history were obtained through interview and medical history was procured from medical records. Periodontal parameters were recorded by a calibrated examiner.Statistical analysis was done using SPSS-15 software. Odds ratio was calculated to assess the strength of association and multivariate regression model was used to adjust the effect of confounders.
Results: There was no significant difference in the prevalence of periodontitis between the four groups. None of the periodontal parameters showed a significant risk for any of the adverse pregnancy outcomes except for the crude association observed between the presence of periodontitis and normal term low birth weight babies. After the adjustment for the possible confounding factors, the risk became insignificant whereas, factors such as anaemia,foetal anomaly, PROM, age, diet, educational status, gender of the newborn, income and no of pre-natal visits were the significant risk factors for adverse pregnancy outcomes.
Conclusions: This study concluded that periodontitis is not a significant independent risk factor for Preterm and/or low birth weight babies among South Indian population.
IADR/AADR/CADR General Session
2017 IADR/AADR/CADR General Session (San Francisco, California)
San Francisco, California
2017
0965
Periodontal Research-Diagnosis/Epidemiology
  • Varghese, Sheeja  ( Saveetha Dental College , Chennai , Tamil Nadu , India )
  • Govindhasamy, Rohini  ( CSI college of dental science and research , Madurai , TAMIL NADU , India )
  • Jayakumar, Nadathur  ( Saveetha Dental College , Chennai , Tamil Nadu , India )
  • NONE
    Poster Session
    Periodontal Research-Diagnosis/Epidemiology I
    Thursday, 03/23/2017 , 11:00AM - 12:15PM
    Distribution of characteristics of study groups
    VariableNormal term Normal birth (Group I) N(%)Pre term Normal birth weight (Group II) N(%)Pre term Low birth weight (Group III) N(%)Normal term Low birth weight (Group IV) N(%)
    Area-Rural300 (27.3%)98 (24.5%)281 (28.1%)246 (24.6%)
    Area-Urban800 (72.7%)302 (75.5%)719 (71.9%)754 (75.4%)
    Age 18-24 yrs682 (62%)324 (81%)704 (70.4%)581 (58.1%)
    Age >25yrs418 (38%)76 (19%)296 (29.6%)419 (41.9%)
    Income 444 (40.4%)85 (20.2%)417 (41.7%)586 (58.6%)
    Income >Rs 3000656 (59.6%)315 (79.8%)583 (58.3%)414 (41.4%)
    Diet-veg439 (39.6%)318 (79.5%)530 (53%)478 (47.8%)
    Diet-Non veg661 (60.4%)82 (20.5%)470 (47%)522 (52.2.%)
    Educational status-None/Primary237 (21.5%)147 (36.8%)644 (64.4%)584 (58.4%)
    Educational status-Secondary or more863 (78.5%)253 (63.2%)356 (35.6%)416 (41.6%)
    Hypertension-yes20 (1.8%)8 (2%)14 (1.4%)9 (0.9%)
    Hypertension-No1080 (98.2%)392 (98%)986 (98.6%)991 (99.1%)
    Anemia-Present147 (13.4%)44 (11%)368 (36.8%)248 (24.8%)
    Anemia-Absent953 (86.6%)356 (89%)632 (63.2%)953 (95.3%)
    Respiratory disorder-Present11 (1%)14 (1.4%)9 (0.9%)12 (1.2%)
    Respiratory disorder-Absent1089 (99%)986 (98.6%)991 (99.1%)988 (98.8%)
    No of prenatal visits<474 (6.7%)70 (17.5%)51 (5.1%)18 (1.8%)
    No of prenatal visits>41026 (93.3%)330 (82.5%)949 (94.9%)982 (98.2%)
    H/o previous pre term delivery-Yes9 (0.8%)54 (13.5%)97 (9.7%)58 (5.8%)
    H/o previous pre term delivery-no1091 (99.2%)346 (86.5%)903 (90.3%)942 (94.2%)

    Distribution of characteristics of study groups (contd)
    VariablesNormal term Normal birth weight (Group I) N (%)Pre term Normal birth weight (Group II) N (%)Pre term Low birth weight (Group III) N (%)Normal term low birth weight (Group IV) N (%)
    H/o previous low birth weight-present2 (0.2%)2 (0.5%)19 (1.9%)54 (5.4%)
    H/o previous low birth weight-absent1098 (99.8%)398 (99.5%)991 (99.1%)946 (94.6%)
    Foetal anomaly-Present4 (0.4%)2 (0.3%)33 (3.3%)18 (1.8%)
    Foetal anomaly-Absent1096 (99.6%)398 (99.7%)997 (99.7%)982 (98.2%)
    Uterine anomaly-Present5 (0.4%)26 (6.5%)46 (4.6%)16 (1.6%)
    Uterine anomaly-Absent1095 (99.6%)374 (93.5%)954 (95.4%)984 (98.4%)
    Premature rupture of membranes (PROM)-Present27 (2.5%)43 (10.8%)373 (37.3%)45 (4.5%)
    Premature rupture of membranes (PROM)-Absent1073 (97.5%)357 (89.2%)627 (62.7%)955 (95.5%)
    Infection during pregnancy-Yes6 (0.5%)24 (6%)19 (1.9%)30 (3%)
    Infection during pregnancy-No1094 (99.5%)376 (94%)1081 (99.1%)970 (97%)
    Gender of the newborn-Male550 (50%)


    298 (74.5%)593 (59.3%)517 (51.7%)
    Gender of the newborn-Female550 (50%)102 (25.5%)407 (40.7%)483 (48.3%)
    maternal peridontitis-Yes603 (54.8%)209 (52.3%)538 (53.8%)594 (59.4%)
    Maternal periodontitis-No497 (45.2%)191 (47.8%)462 (46.2%)406 (40.6%)
    Bleeding score <50%934 (84.9%)163 (40.7%)856 (85.6%)821 (82.1%)
    Bleeding score >50%166 (15.1%)237 (59.3%)144 (14.4%)179 (17.9%)
    Plaque score<50%910 (82.7%)155 (38.8%)826 (82.6%)800 (80%)
    Plaque score>50%190 (17.3%)245 (61.2%)174 (17.4%)200 (20%)
    Mild periodontitis205 (18.6%)88 (22%)226 (22.6%)262 (26.2%)
    Moderate peridontitis200 (18.2%)72 (18%)163 (16.3%)185 (18.5%)
    Severe periodontitis198 (18%)49 (12.3%)163 (16.3%)185 (18.5%)

    Adjusted and unadjusted odds ratio between the groups
    VariableGroup II vs Group I
    Unadjusted odds ratio and p-value
    Group II vs Group I
    adjusted odds ratio and p-value
    Group III vs Group I
    Unadjusted odds ratio and p-value
    Group III vs Group I
    Adjusted odds ratio and p-value
    Group IV vs Group I
    Unadjusted odds ratio and p-value
    Group IV vs Group I
    adjusted odds ratio and p-value
    Age2.613 (0.000*)2.631 (0.000*)1.458 (0.000*)1.143 (0.036*)0.850 (0.658)-
    Area0.865 (0.282)-1.042 (0.672)-0.870 (0.163)-
    Income0.216 (0.000*)0.060 (0.000*)1.057 (0.534)0.841 (0.207)2.091 (0.000*)1.338 (0.000*)
    Education (None/Primary)2.116 (0.000*)1.325 (0.183)2.013 (0.000*)1.220 (0.020*)2.013 (0.000*)1.356 (0.020*)
    Hypertension1.102 (0.830)-0.767 (0.048*)---
    Diet5.839 (0.000*)8.515 (0.000*)-2.168 (0.000*)1.379 (0.000*)0.810 (0.116)
    Anemia0.801 (0.225)-3.775 (0.000*)2.266 (0.000*)2.367 (0.000*)1.317 (0.000*)
    No of prenatal visits2.941 (0.000*)3.819 (0.000*)0.705 (0.115)-0.254 (0.000*)0.258 (0.000*)
    H/O preterm delivery18.916 (0.000*)12.022 (0.000*)13.022 (0.000*)3.306 (0.000*)2.270 (0.000*)0.941 (0.000*)
    Foetal anomaly0.867 (0.736)0.687 (0.736)9.531 (0.000*)4.762 (0.011*)5.022 (0.000*)1.876 (0.000*)
    Uterine anomaly19.048 (0.000*)9.603 (0.000*)13.513 (0.000*)2.982 (0.000*)--
    PROM4.787 (0.010*)2.661 (0.183)23.672 (0.000*)12.771 (0.000*)1.875 (0.000*)0.590 (0.102)
    Infection during pregnancy11.638 (0.000*)7.857 (0.019*)1.656 (0.335)-6.809 (0.000*)3.778 (0.000*)
    Gender2.922 (0.008*)-1.457 (0.000*)1.115 (0.000*)1.457 (0.070)-
    Periodontitis0.902 (0.378)0.712 (0.285)0.960 (0.640)0.757 (0.185)1.206 (0.034)0.940 (0.775)
    Bleeding score0.834 (0.126)1.585 (0.659)0.947 (0.656)1.236 (0.777)0.786 (0.083)0.238 (0.210)
    Plaque score0.776 (0.229)0.289 (0.229)0.994 (0.939)0.356 (0.172)1.197 (0.108)1.242 (0.189)
    Mild periodontitis1.115 (0.069)0.595 (0.069)1.202 (0.113)0.581 (0.065)1.561 (0.000*)1.341 (0.189)
    Moderate periodontitis0.930 (0.001*)0.332 (0.001*)0.896 (0.375)0.544 (0.15)1.124 (0.336)1.417 (0.211)
    Severe periodontitis0.643 (0.000*)0.254 (0.000*)0.835 (0.121)0.435 (0.067)0.907 (0.445)0.911 (0.719)