IADR Abstract Archives
Iowa Biorepository: A Unique Opportunity for Collaborative Research
Objectives: To establish a biorepository that will combine biological materials, dental and medical records in order to improve quality of care provided to the patients and enhance broader quality research across the University of Iowa medical and dental facilities; and to make these data and biological materials available to researchers in order to conduct ground breaking research to deliver personalized precision medicine and thereby improve patients’ health.
Methods: Institutional Review Board approval was obtained on 3/18/2016, Progeny software was installed on 9/23/2016. Patients visiting the dental clinics at the College of Dentistry are invited to participate in the biorepository. Samples collected included saliva, cheek swabs, gingival crevicular fluid, oral soft tissues, and oral hard tissues (bone and teeth).
Results: Iowa Biorepository combines a DNA/RNA bank with dental and medical records. It combines data from the University of Iowa Healthcare Epic® hospital information system, the College of Dentistry University of Iowa Electronic Dental Records Axium® database, and Progeny®, a software program that incorporates Clinical, Family History, Lab (data and sample management) with an integrated pedigree drawing component.
As of today, One hundred and eighty-nine subjects consented and donated biological specimens (73 males and 116 females).
Conclusions: The Iowa Biorepositroy is an ongoing project and remains a work in progress despite significant strides over the past year. Iowa’s Biorepository will provide support for various research areas such as: Bioengineering, Tissue Engineering, Stem Cells, Craniofacial, Oral Biology, Genetics and Dental Development; Immunology, Microbiology, Caries and Microbiome Research; Public Health & Epidemiology.
Keys to success of the biorepository has been Leadership support, cooperative team atmosphere, financial and administrative support, and integrated IT systems.
In addition to collaborative research, this initiative will fully embrace the era of personalized medicine using the knowledge of genetics and clinical influences to bring about focused and improved clinical care.
Methods: Institutional Review Board approval was obtained on 3/18/2016, Progeny software was installed on 9/23/2016. Patients visiting the dental clinics at the College of Dentistry are invited to participate in the biorepository. Samples collected included saliva, cheek swabs, gingival crevicular fluid, oral soft tissues, and oral hard tissues (bone and teeth).
Results: Iowa Biorepository combines a DNA/RNA bank with dental and medical records. It combines data from the University of Iowa Healthcare Epic® hospital information system, the College of Dentistry University of Iowa Electronic Dental Records Axium® database, and Progeny®, a software program that incorporates Clinical, Family History, Lab (data and sample management) with an integrated pedigree drawing component.
As of today, One hundred and eighty-nine subjects consented and donated biological specimens (73 males and 116 females).
Conclusions: The Iowa Biorepositroy is an ongoing project and remains a work in progress despite significant strides over the past year. Iowa’s Biorepository will provide support for various research areas such as: Bioengineering, Tissue Engineering, Stem Cells, Craniofacial, Oral Biology, Genetics and Dental Development; Immunology, Microbiology, Caries and Microbiome Research; Public Health & Epidemiology.
Keys to success of the biorepository has been Leadership support, cooperative team atmosphere, financial and administrative support, and integrated IT systems.
In addition to collaborative research, this initiative will fully embrace the era of personalized medicine using the knowledge of genetics and clinical influences to bring about focused and improved clinical care.