IADR Abstract Archives
An Evaluation of the Effectiveness and Predictability of Titanium Prepared Platelet Rich Fibrin and Subepithelial Connective Tissue Graft for Management of Multiple Gingival Recession Defects
Objectives: A novel platelet-rich product called titanium prepared platelet-rich fibrin (T-PRF) has stronger and thicker fibrin than that of the classic glass tube prepared platelet-rich fibrin. Strong fibrin structure is important to extend the time for resorption of fibrin in-vivo, and increase the release time of growth factors. There has been no study to date comparing the effectiveness and predictability of T-PRF with that of subepithelial connective tissue graft (CTG), the gold standard for root coverage. The purpose of this 12-months randomized controlled clinical trial is to compare the effects of autogenous T-PRF and CTG at multiple gingival recessions.
Methods: 34 patients were referred to our clinic with a total of 114 Miller Class I/II gingival recessions represented that exposed root surfaces showed abrasion defects, indicating toothbrushing trauma as the causative factor. Recessions were randomly treated with T-PRF (63 teeth) or CTG (51 teeth) and modified tunnel technique. The following clinical measurements were taken before the surgery and at 6 months and 12 months follow-up examination: probing depth, clinical attachment level, amount of keratinized tissue (KT), gingival thickness and recession depth. Also Visual Analog Scale, healing index were evaluated.
Results: After 12 months, mean root coverage was 93.29% and 93.22% in the T-PRF and CTG groups, respectively. CTG (0.53 mm) has increased gingival thickness more than T-PRF (0.13 mm) in 12 th months when compared to baseline. The increase in KT 12 th months in T-PRF (1.97 mm) group was more statistically significant when compared to CTG (0.75 mm) group.
Conclusions: Within the limits of this study, the results demonstrated that T-PRF membrane is safe and effective in a treatment of multiple Miller Class I/II gingival recession defects. T-PRF can be prefered as a good autogenous alternative to CTG, which is the gold standard for root coverage.
Methods: 34 patients were referred to our clinic with a total of 114 Miller Class I/II gingival recessions represented that exposed root surfaces showed abrasion defects, indicating toothbrushing trauma as the causative factor. Recessions were randomly treated with T-PRF (63 teeth) or CTG (51 teeth) and modified tunnel technique. The following clinical measurements were taken before the surgery and at 6 months and 12 months follow-up examination: probing depth, clinical attachment level, amount of keratinized tissue (KT), gingival thickness and recession depth. Also Visual Analog Scale, healing index were evaluated.
Results: After 12 months, mean root coverage was 93.29% and 93.22% in the T-PRF and CTG groups, respectively. CTG (0.53 mm) has increased gingival thickness more than T-PRF (0.13 mm) in 12 th months when compared to baseline. The increase in KT 12 th months in T-PRF (1.97 mm) group was more statistically significant when compared to CTG (0.75 mm) group.
Conclusions: Within the limits of this study, the results demonstrated that T-PRF membrane is safe and effective in a treatment of multiple Miller Class I/II gingival recession defects. T-PRF can be prefered as a good autogenous alternative to CTG, which is the gold standard for root coverage.