Periosteal Pedicle Flap - Plateletes Rich Fibrin for Periodontal Regeneration

Objectives: The use of autogenous graft materials has been recorded to be a gold standard in regenerative therapy. This study directed toward evaluation of 2 autogenous regenerative materials, marginal periosteal pedicle graft (MPP) and platelet rich fibrin (PRF) as a membrane barriers for treating intrabony defects. In spite of its reported significant clinical outcomes, the limited availability of the periosteum makes it necessary to evaluate other autogenous alternatives such as PRF that could offer predictable outcomes.
Methods: In a split mouth design10 patients with severe chronic periodontitis and at least 2 sites ≥4 mm intrabony defect had participated in this randomized clinical study. Subjects were randomly divided into2 groups, Group 1 (MPP) defect coverage with xenograft defect fill, Group 2 (PRF) defect coverage with xenograft defect fill. Clinical and radiographic measurements were at 3, 6 and 9 months postoperatively.
Results: Clinical attachment gain was 2.7 ± 1.1, 3 ± 1.3 for MPP and PRF respectively. Intrabony reduction was-1.1 ± 0.3 and -1.4 ± 0.7 for MPP and PRF respectively.
Conclusions: Both platelets rich fibrin and marginal periosteal pedicle graft have a significant healing potential as a regenerative technique in treating periodontal defects. Membrane exposure was not likely to develop following PRF and MPP grafts suggesting a more tissue friendly behavior of these two autogenous grafts.