IADR Abstract Archives
Changes in Peri-implant Tissue and Microcirculation After Photo Functionalization
Objectives: Ultraviolet photo functionalization is a new method for improving the surface characteristics of titanium implants. The purpose of this study was to examine the regeneration of microcirculation and bone formation after photo functionalization in a morphological analysis.
Methods: Six beagle dogs were used in this study. The use of experimental animals was in accordance with the Animal Care Committee guidelines of our institution. Mandibular premolars were extracted and a titanium screw implant (length 8 mm, diameter 3.3 mm, SLA) immediately inserted into each extraction socket. The implant on one side was photo functionalized with UV light for 15 minutes before placing the implant (UV group). The other side was served as the control group. Two dogs 14, 30, and 60 days after surgery, synthetic resin was injected into the inferior alveolar arteries. The microvascular resin cast models were observed by light and scanning electron microscopy.
Results: After 14 days, peri-implant bone was not observed clearly along the implant surface in the control group. Newly formed blood vessels were observed between the bone implant interface. In the UV group, thin peri-implant bone was observed. Blood vessels were buried under the porous new bone tissue. After 30 days, thin peri-implant bone and bone trabeculae were regenerated in the control group. Peri-implant bone was thicker in the UV group than in the control group. In both groups, a vascular network was observed in the bone marrow space. After 60 days, peri-implant bone was thicker in the UV group than in the control group.
Conclusions: In the early stages, vascularization was guided. New bone formation occurred surrounding the vascular network. The photo functionalization group always had thicker peri-implant bone than the control group. The regeneration of blood vessels was also accelerated in the UV group. Therefore, the results suggest that photo functionalization is effective for osseointegration.
Methods: Six beagle dogs were used in this study. The use of experimental animals was in accordance with the Animal Care Committee guidelines of our institution. Mandibular premolars were extracted and a titanium screw implant (length 8 mm, diameter 3.3 mm, SLA) immediately inserted into each extraction socket. The implant on one side was photo functionalized with UV light for 15 minutes before placing the implant (UV group). The other side was served as the control group. Two dogs 14, 30, and 60 days after surgery, synthetic resin was injected into the inferior alveolar arteries. The microvascular resin cast models were observed by light and scanning electron microscopy.
Results: After 14 days, peri-implant bone was not observed clearly along the implant surface in the control group. Newly formed blood vessels were observed between the bone implant interface. In the UV group, thin peri-implant bone was observed. Blood vessels were buried under the porous new bone tissue. After 30 days, thin peri-implant bone and bone trabeculae were regenerated in the control group. Peri-implant bone was thicker in the UV group than in the control group. In both groups, a vascular network was observed in the bone marrow space. After 60 days, peri-implant bone was thicker in the UV group than in the control group.
Conclusions: In the early stages, vascularization was guided. New bone formation occurred surrounding the vascular network. The photo functionalization group always had thicker peri-implant bone than the control group. The regeneration of blood vessels was also accelerated in the UV group. Therefore, the results suggest that photo functionalization is effective for osseointegration.