IADR Abstract Archives
Enamel Demineralization Prevention by Eight Treatments in Full-banded Orthodontic Patients
Objectives: Document clinical performance of eight treatments in enamel demineralization prevention.
Methods: Practice-based, controlled clinical trial. 328 patients (95% completed), 9-18yrs, 56% male, none users of fluoride (F) supplements or F-water, all users of OTC-F dentifrice, all full-banded-orthodontic cases. Assigned randomly to 8 groups: daily (1)Xylitol gum-tablets-dentifrice (Epic) 6gm/day; F-2x/day (2)Clinpro5000 ppmF; (3)PreviDent5000 ppmF Plus or Booster; (4)MI-Paste-Plus amorphous calcium phosphate+900ppmF; treatment each 6-8 weeks (5)HealOzone 2100ppm O3-gas 1min/arch; (6)VarnishAmerica 5%NaF-varnish all tooth surfaces; combined (7)VarnishAmerica-PreviDent5000; control (8)patient’s own OTC-F dentifrice and regimen. Before banding and each 6-8 weeks recorded: saliva pH and flow rate, oral hygiene, compliance, ATPase activity, foods eaten, full-color close-up images of all anterior and pre-molar teeth. Demineralization defined by visual appearance (none, light-to-moderate, severe) and quantified/tooth (ImagePro-Plus, MediaCybernetics) on clinical photographs before, 7days post-debanding, 1yr after treatment discontinued. Statistics: Generalized linear mixed models; teeth clustered by patient.
Results: See Image-1 below.
PreviDent5000 Plus and Booster not different; both had significantly less demineralization. Demineralization exceeding Control: Clinpro5000, MI-Paste-Plus, Xylitol. All patients had visually apparent demineralization. Only 5-23% of teeth within the 8 groups had no visible demineralization.
Demineralization predictors: treatment (<0.000), tooth location (<0.000), time in orthodontics (<0.000), age (<0.000), hygiene (0.013), before-study F-supplement duration (0.014). Post-treatment natural resolution of demineralization not related to treatment (0.489), but to demineralization severity and tooth location (both <0.000).
Conclusions: All treatments tested failed to prevent all enamel demineralization in any one patient or treatment group.
Methods: Practice-based, controlled clinical trial. 328 patients (95% completed), 9-18yrs, 56% male, none users of fluoride (F) supplements or F-water, all users of OTC-F dentifrice, all full-banded-orthodontic cases. Assigned randomly to 8 groups: daily (1)Xylitol gum-tablets-dentifrice (Epic) 6gm/day; F-2x/day (2)Clinpro5000 ppmF; (3)PreviDent5000 ppmF Plus or Booster; (4)MI-Paste-Plus amorphous calcium phosphate+900ppmF; treatment each 6-8 weeks (5)HealOzone 2100ppm O3-gas 1min/arch; (6)VarnishAmerica 5%NaF-varnish all tooth surfaces; combined (7)VarnishAmerica-PreviDent5000; control (8)patient’s own OTC-F dentifrice and regimen. Before banding and each 6-8 weeks recorded: saliva pH and flow rate, oral hygiene, compliance, ATPase activity, foods eaten, full-color close-up images of all anterior and pre-molar teeth. Demineralization defined by visual appearance (none, light-to-moderate, severe) and quantified/tooth (ImagePro-Plus, MediaCybernetics) on clinical photographs before, 7days post-debanding, 1yr after treatment discontinued. Statistics: Generalized linear mixed models; teeth clustered by patient.
Results: See Image-1 below.
PreviDent5000 Plus and Booster not different; both had significantly less demineralization. Demineralization exceeding Control: Clinpro5000, MI-Paste-Plus, Xylitol. All patients had visually apparent demineralization. Only 5-23% of teeth within the 8 groups had no visible demineralization.
Demineralization predictors: treatment (<0.000), tooth location (<0.000), time in orthodontics (<0.000), age (<0.000), hygiene (0.013), before-study F-supplement duration (0.014). Post-treatment natural resolution of demineralization not related to treatment (0.489), but to demineralization severity and tooth location (both <0.000).
Conclusions: All treatments tested failed to prevent all enamel demineralization in any one patient or treatment group.
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