IADR Abstract Archives
Sinus Lift by Newly Forming Bone Graft: A Proof-of-principle Study
Objectives: The aim of this study is to evaluate the effects of newly forming bone graft (NFBG) and inorganic bovine bone (IBB) mixture in augmenting bone height in sinus lift procedures.
Methods: Both genders individuals aged 25-60 years showing absence of a single tooth in the upper posterior region were recruited. To be included, patients should present a remaining subantral bone height of 2-9 mm. Sites were randomly allocated to test (1:2 or 1:3 NFB+IBB; n= 7) or control (IBB; n= 6) groups. Bone volume was evaluated in computed tomography (CT) obtained at baseline and 6 months post-operative. Implants were installed after 6 months, when a bone core biopsy was obtained with a 2mm trephine bur, allowing histologic and histomorphometric analysis.
Results: No implant was lost up to prosthesis installation, resulting in a 100% survival rate. Analysis of bone height in CT images at baseline and 6 months by t test showed a similar increase of bone height in both groups (test: 11.22 ± 0.60 vs. control: 11.82 ± 0.69; p=0.06). The histologic analysis of tissue reaction around and between non-vital particles showed no significant differences between groups (Mann-Whithney; p> 0.05). Histomorpohometric analysis showed higher percentage of vital bone (31.42% ± 11.13% vs. 16.38% ± 10.14%; p=0.0005), and less percentage of non-vital particles (1.32% ± 2.34% vs. 3.15% ± 3.31%; p= 0.03) and connective tissue (27.65% ± 12.34% vs. 35.02% ± 13.16; p= 0.02) at test than controls. A greater mean non-vital particles diameter was observed at controls (t test; p= 0.0294), although no significant differences between were observed in the direct contact of new bone and particles (p> 0.05).
Conclusions: These results suggested that NFBG+IBB promotes gain in bone height, resulting in a greater area occupied by vital bone than those observed in maxillary sinus augmented by IBB.
Methods: Both genders individuals aged 25-60 years showing absence of a single tooth in the upper posterior region were recruited. To be included, patients should present a remaining subantral bone height of 2-9 mm. Sites were randomly allocated to test (1:2 or 1:3 NFB+IBB; n= 7) or control (IBB; n= 6) groups. Bone volume was evaluated in computed tomography (CT) obtained at baseline and 6 months post-operative. Implants were installed after 6 months, when a bone core biopsy was obtained with a 2mm trephine bur, allowing histologic and histomorphometric analysis.
Results: No implant was lost up to prosthesis installation, resulting in a 100% survival rate. Analysis of bone height in CT images at baseline and 6 months by t test showed a similar increase of bone height in both groups (test: 11.22 ± 0.60 vs. control: 11.82 ± 0.69; p=0.06). The histologic analysis of tissue reaction around and between non-vital particles showed no significant differences between groups (Mann-Whithney; p> 0.05). Histomorpohometric analysis showed higher percentage of vital bone (31.42% ± 11.13% vs. 16.38% ± 10.14%; p=0.0005), and less percentage of non-vital particles (1.32% ± 2.34% vs. 3.15% ± 3.31%; p= 0.03) and connective tissue (27.65% ± 12.34% vs. 35.02% ± 13.16; p= 0.02) at test than controls. A greater mean non-vital particles diameter was observed at controls (t test; p= 0.0294), although no significant differences between were observed in the direct contact of new bone and particles (p> 0.05).
Conclusions: These results suggested that NFBG+IBB promotes gain in bone height, resulting in a greater area occupied by vital bone than those observed in maxillary sinus augmented by IBB.